DiAna, an ImageJ tool for object-based 3D co-localization and distance analysis
DiAna, an ImageJ tool for object-based 3D co-localization and distance analysis
复制标题
DOI:
10.1016/j.ymeth.2016.11.016
复制
发表时间:
2017-02-15
期刊:
影响因子:
4.8
通讯作者:
Heck, Nicolas
中科院分区:
文献类型:
--
作者:
Gilles, Jean-Francois;Dos Santos, Marc;Heck, Nicolas
We present a new plugin for Image) called DiAna, for Distance Analysis, which comes with a user-friendly interface. DiAna proposes robust and accurate 3D segmentation for object extraction. The plugin performs automated object-based co-localization and distance analysis. DiAna offers an in-depth analysis of co-localization between objects and retrieves 3D measurements including co-localizing volumes and surfaces of contact. It also computes the distribution of distances between objects in 3D. With DiAna, we furthermore introduce an original method, which allows for estimating the statistical significance of object co-localization. DiAna offers a complete and intuitive 3D image analysis tool for biologists. (C) 2016 Elsevier Inc. All rights reserved.