Total Fluid Administration and Weight Loss during the First 2 Weeks in Infants Randomized to Early Enteral Feeding after Extremely Preterm Birth.
Total Fluid Administration and Weight Loss during the First 2 Weeks in Infants Randomized to Early Enteral Feeding after Extremely Preterm Birth.
复制标题
极早产后随机接受早期肠内喂养的婴儿前两周的总液体摄入量和体重减轻。
DOI：
10.1159/000527430
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发表时间：
2023
期刊：
影响因子：
2.5
通讯作者：
Salas,ArielA
中科院分区：
文献类型：
--
作者：
Durham,Leandra;Gunawan,Emily;Nguyen,Kelly;Reeves,Audrey;Shukla,Vivek;Salas,ArielA
背景：随机试验尚未报道喂养量的早期进展对极早产儿（≤28周）体液平衡和神经发育的影响。方法：对60名极早产儿的液体、电解质和神经发育数据进行分析，这些极早产儿被随机分配接受1天（早期喂养组）或4天（晚期喂养组）营养喂养量（20-24 mL/kg/day）。结果：随机分配到早期喂养组的婴儿在出生后的前14天接受较少的胃肠外液体，产生较少的尿量，体重减轻较少。7分的认知得分和0.5的差异，年龄的体重z分数有利于早期喂养group.Conclusions：在极早产儿，早期肠内喂养与总液体管理和出生后的前2周内体重减轻较少的差异没有达到统计学意义。这些短期的影响可能会带来长期的好处。
Background:Randomized trials have not reported the effects of the early progression of feeding volumes on fluid balance and neurodevelopment among infants born extremely preterm (≤28 weeks).Method:Fluid, electrolyte, and neurodevelopment data of 60 extremely preterm infants randomly assigned to receive either 1 (early feeding group) or 4 days (late feeding group) of trophic feeding volumes at 20–24 mL/kg/day were analyzed.Results:Infants randomized to the early feeding group received less parenteral fluids, generated lower urine volumes, and had less excessive weight loss during the first 14 days after birth. The 7-point difference in cognitive scores and the 0.5 difference in weight-for-age z-scores favoring the early feeding group did not reach statistical significance.Conclusions:In extremely preterm infants, early enteral feeding is associated with less total fluid administration and with less excessive weight loss during the first 2 weeks after birth. These short-term effects could have long-lasting benefits.