Sense of muscular effort and somesthetic afferent information in humans.

Sense of muscular effort and somesthetic afferent information in humans.
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人类的肌肉力量感和某种感觉传入信息。

DOI:
10.1139/y95-033
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发表时间:
1995
影响因子:
2.1
通讯作者:
Shadmehr,R
Shadmehr,R
中科院分区:
医学4区
文献类型:
--
作者:
Sanes,JN;Shadmehr,R

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对患有大纤维躯体感觉神经病的患者进行的实验室和临床观察表明,这些患者严重无法设定维持静态姿势和再现简单运动所需的准确肌肉活动的强直或阶段性水平。这些观察结果表明,躯体感觉有助于运动输出的感觉,以前认为是由推论放电的中枢机制介导的。我们回顾了描述体重匹配任务中的心理物理表现的数据,并讨论了由大纤维感觉神经病患者和正常对照组完成任务的新实验。综合起来,数据表明,患有外周感觉缺陷的患者表现出肌肉力量感受损以及主动运动的后果。此外,体重匹配的数据表明,努力感中断的基础与无法将心理物理决策与伴随的肌肉活动相关联有关。在新的实验中,患有大纤维感觉神经病的患者通过指向主动达到的手臂终点的匹配准确性降低了。集体结果表明,运动输出的欣赏部分是由躯体感觉传入系统的外周返回介导的。关键词:肌肉力量,感觉神经病,运动控制,人类。
Laboratory and clinical observations of patients with a large-fiber somatic sensory neuropathy indicate a dramatic inability of these patients to set accurate tonic or phasic levels of muscle activity needed to maintain static postures and to reproduce simple movements. These observations suggest that somatic sensation contributes to sensations of motor output, previously thought to be mediated by central mechanisms of corollary discharge. We review data describing psychophysical performance on weight-matching tasks and discuss new experiments on reaching tasks done by patients with a large-fiber sensory neuropathy and normal controls. In combination, the data show that patients with peripheral sensory deficits exhibit an impaired sense of muscular effort and the consequences of active movement. In addition, the data on weight matching indicate that the basis of disrupted effort sense relates to an inability to correlate psychophysical decisions with concomitant muscle activity. In new experiments, accuracy to match actively achieved arm end points by pointing was decreased in patients with large-fiber sensory neuropathy. The collective results suggest that appreciation of motor output is mediated in part by peripheral return from somatic sensory afferent systems.Key words: muscular effort, sensory neuropathy, motor control, human.
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