Effects of motion on high frame rate contrast enhanced echocardiography and its correction
Effects of motion on high frame rate contrast enhanced echocardiography and its correction
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DOI：
10.1109/ultsym.2017.8092362
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发表时间：
2017-09
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影响因子：
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通讯作者：
M. Toulemonde;W. C. Duncan;A. Stanziola;V. Sboros;Yuanwei Li;R. Eckersley;Shengtao Lin;M. Tang;M. Butler
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文献类型：
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作者：
M. Toulemonde;W. C. Duncan;A. Stanziola;V. Sboros;Yuanwei Li;R. Eckersley;Shengtao Lin;M. Tang;M. Butler
使用微泡造影剂的超声造影(CE)极大地提高了我们评估心脏功能的能力，包括心肌灌注成像和定量。然而，在传统的逐行扫描的CE技术中，帧速率被限制在每秒数十帧，并且图像质量较低。高帧频(HFR)超声的最新研究工作表明，在非对比剂心脏成像中，帧速率有了显著的改善。但在较高的帧速率下，HFR CE图像的相干合成会因微泡的运动而显示出一些伪影。在这项工作中，我们在仿真中演示了这种运动对复合HFR CE的影响，然后将运动校正算法应用于从绵羊左心室(LV)腔获取的活体数据。它表明，即使在LV内部发现快速流动，对比度也至少提高了100%。
Contrast echocardiography (CE) ultrasound with microbubble contrast agents have significantly advanced our capability in assessing cardiac function, including myocardium perfusion imaging and quantification. However in conventional CE techniques with line by line scanning, the frame rate is limited to tens of frames per second and image quality is low. Recent research works in high frame-rate (HFR) ultrasound have shown significant improvement of the frame rate in non-contrast cardiac imaging. But with a higher frame rate, the coherent compounding of HFR CE images shows some artifacts due to the motion of the microbubbles. In this work we demonstrate the impact of this motion on compounded HFR CE in simulation and then apply a motion correction algorithm on in-vivo data acquired from the left ventricle (LV) chamber of a sheep. It shows that even if with the fast flow found inside the LV, the contrast is improved at least 100%.