Relationship between changes in hearing function and volumes of endolymphatic hydrops after endolymphatic sac drainage
Relationship between changes in hearing function and volumes of endolymphatic hydrops after endolymphatic sac drainage
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DOI：
10.1080/00016489.2019.1630757
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发表时间：
2019-07-04
影响因子：
1.4
通讯作者：
Kitahara, Tadashi
中科院分区：
文献类型：
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作者：
Ito, Taeko;Inui, Hiroshi;Kitahara, Tadashi
背景：内淋巴囊引流（ELSD）可能对内淋巴积水（EH）有积极作用，并可能有助于保护内耳功能。然而，ELSD 后 EH 音量变化与听力功能之间的关系尚未描述。目的：我们旨在揭示 ELSD 后与听力和 EH 变化相关的因素。材料和方法：纳入 21 名接受 ELSD 的患者。静脉注射钆增强后4小时进行纯音测听和3-T磁共振成像（MRI），分别在术前和2年后进行。为了表征内淋巴空间 (ELS)，我们测量了总液体 (TFS) 和 ELS 的体积，并计算了 ELS 与 TFS 的比率（ELS 比率）。结果：听力改善患者的ELS比率术前为18.5±11.4%，术后为23.9±14.3%。对于没有变化的患者，之前为29.7 +/- 10.8%，之后为29.4 +/- 9.5%；对于听力功能恶化的患者，之前为22.7 +/- 7.5%，之后为27.2 +/- 13.4%。结论：我们发现 ELSD 后听力功能的变化与 EH 音量之间没有相关性。
Background: Endolymphatic sac drainage (ELSD) may have a positive effect on endolymphatic hydrops (EH) and may help to preserve inner ear function. However, the relationship between changes in EH volumes and hearing function after ELSD has not been described. Objectives: We aimed to reveal the factors related to changes in hearing and EH following ELSD. Material and Methods: Twenty-one patients who received ELSD were enrolled. Pure tone audiometry and 3-T magnetic resonance imaging (MRI) 4 h after intravenous injection of gadolinium enhancement were performed just before surgery and 2 years later. To characterize the endolymphatic space (ELS), we measured the volume of the total fluid (TFS) and ELS and calculated the ratio of ELS to TFS (ELS ratio). Results: The ELS ratio of the patients who showed hearing improvement was 18.5 +/- 11.4% before surgery and 23.9 +/- 14.3% after. For those with no change, it was 29.7 +/- 10.8% before and 29.4 +/- 9.5% after, and in patients with worsened hearing function it was 22.7 +/- 7.5% before and 27.2 +/- 13.4% after. Conclusion: We found no correlation between the changes in hearing function and the volume of EH after ELSD.