INCREASED SUSCEPTIBILITY TO MEMORY INTRUSIONS AND THE STROOP INTERFERENCE EFFECT DURING ACUTE MARIJUANA INTOXICATION
INCREASED SUSCEPTIBILITY TO MEMORY INTRUSIONS AND THE STROOP INTERFERENCE EFFECT DURING ACUTE MARIJUANA INTOXICATION
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DOI：
10.1007/bf00690920
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发表时间：
1987-01-01
影响因子：
3.4
通讯作者：
JONES, RT
中科院分区：
文献类型：
--
作者：
HOOKER, WD;JONES, RT
在双盲交叉实验中评估大麻引起的急性记忆障碍。12名男性在间隔1-3周的2天内以平衡顺序吸食含有1.2%脱拉-9-四氢大麻酚（THC）或大麻素耗尽的大麻（安慰剂）的NIDA供应的香烟。练习，吸烟前和吸烟后的测试会话进行了起搏听觉串行添加测试，Stroop颜色和单词测试，以及替代形式的兰特记忆电池和控制的口头单词联想测试。一个显着更多的短篇小说遗漏和入侵发生在大麻后延迟自由回忆。即时和持续的注意力，从语义记忆中控制检索，以及阅读和命名颜色的速度没有受到影响。Stroop干扰效应在吸食大麻后显著更大。受试者似乎经历了平行的困难，抑制协会的新材料，并抑制过度学习的反应阅读在一个新的学习任务。联想控制是记忆功能中固有的一种认知过程。
The marijuana-induced acute memory impairment was assessed in a double-blind, crossover experiment. Twelve males smoked NIDA-supplied cigarettes containing 1.2% detla-9-tetrahydrocannabinol (THC) or cannabinoid-exhausted marijuana (placebo) in counterbalanced order on 2 days 1-3 weeks apart. Practice, pre- and postsmoking test session were conducted with the Paced Auditory Serial Addition Test, Stroop Color and Word Test, and alternate forms of the Randt Memory Battery and the Controlled Oral Word Association Test. A significantly greater number of short story omissions and intrusions occurred in delayed free recall after marijuana. Immediate and sustained attention, controlled retrieval from semantic memory, and speed of reading and naming colors were not affected. The Stroop interference effect was significantly greater following marijuana. Subjects appeared to experience parallel difficulties inhibiting associations to the new material and inhibiting the overlearned response of reading in a new learning task. Marijuana may compromise associative control, presumably a cognitive process inherent in memory function.