Primate disconjugate eye movements during the horizontal AVOR in darkness and a plausible mechanism
Primate disconjugate eye movements during the horizontal AVOR in darkness and a plausible mechanism
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DOI：
10.1007/s00221-009-1930-2
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发表时间：
2009-09-01
影响因子：
2
通讯作者：
Galiana, Henrietta L.
中科院分区：
文献类型：
--
作者：
Khojasteh, Elham;Galiana, Henrietta L.
在水平角前庭眼反射（AVOR）引起的头部速度的步骤或脉冲的不共轭的眼睛运动在侧眼动物先前已报告。在这项研究中，我们测量了人类和猴子在黑暗中对持续正弦和伪随机前庭刺激的双眼反应。在我们的实验中使用的前庭刺激具有在120- 200 A度/秒的范围内的峰值速度，在0.17- 0.5Hz的范围内的频率，和在60和75秒之间的持续时间。我们的研究结果表明，一个大的聚散分量的AVOR响应，系统调制的头部速度。我们还检查了我们的结果，颞鼻优势慢眼速度。虽然每个科目都表现出一定程度的方向偏好，我们没有发现一个系统性的更大的眼速度的颞鼻方向在所有科目。在这里，我们提出了这些发现，并讨论至少有两种可能的来源可能会导致在黑暗中的水平旋转VOR的非共轭眼球运动：周边和中央机制。
Disconjugate eye movements during the horizontal angular vestibulo-ocular reflex (AVOR) evoked in response to steps or pulses of head velocity have been previously reported in lateral eyed animals. In this study, we measured binocular responses to sustained sinusoidal and pseudo-random vestibular stimuli in yaw, delivered in darkness, in both human and monkey. The vestibular stimuli used in our experiments had peak velocities in the range of 120-200A degrees/s, frequencies in the range of 0.17-0.5 Hz, and durations between 60 and 75 s. Our results show a large vergence component to the AVOR response that systematically modulated with head velocity. We also examined our results for temporal-nasal preponderance in slow eye velocity. Although each subject showed some degree of directional preference, we did not find a systematically greater eye velocity for temporal-nasal direction across all subjects. Here, we present these findings and discuss that at least two possible sources could result in disconjugate eye movements during the horizontal rotational VOR in darkness: peripheral and central mechanisms.