New modified technique of hydrogel spacer implantation for prostate cancer: a novel method for separation at the prostate apex level under real-time ultrasound guidance
New modified technique of hydrogel spacer implantation for prostate cancer: a novel method for separation at the prostate apex level under real-time ultrasound guidance
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DOI：
10.1007/s10396-022-01254-y
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发表时间：
2022-09-16
影响因子：
1.8
通讯作者：
Ukimura, Osamu
中科院分区：
文献类型：
--
作者：
Narukawa, Tsukasa;Shiraishi, Takumi;Ukimura, Osamu
材料与方法在传统的水凝胶间隔剂注射技术中，术中固定注射针尖的位置，使其保持在前列腺中位（图1a）[4]。另一方面，新的改进技术是将注射针尖从前列腺中水平不断移动回前列腺尖水平，从而在整个前列腺和直肠之间的脂肪组织层空间（包括前列腺尖下）注射足够厚度的间隔剂（图1 a-d）。如果在手术过程中TRUS错过针尖，则此时停止运动。我们分析了2019年9月至2021年8月期间接受间隔器植入质子束治疗（PBT）的181例患者。将间隔器植入技术随机分为两组进行比较：1组采用新方法，2组采用常规方法。统计分析采用Mann-Whitney U检验。
Materials and methodsIn the conventional technique of hydrogel spacer injection, the intra-operative location of the injection needle tip is fixed to maintain it at the mid-prostate level (Fig. 1 a)[4]. On the other hand, the new modified technique is to continuously move the injection needle tip from the mid-prostate level back to the level of the prostate apex, resulting in sufficient thickness of spacer injection throughout the space of the fatty tissue layer between the prostate and rectum including under the prostate apex (Fig. 1 a–d). If the needle tip is missed by TRUS during the procedure, movement is stopped at that time. We analyzed 181 patients who underwent spacer implantation for proton beam therapy (PBT) between September 2019 and August 2021. The spacer implantation techniques were randomly divided into two groups for comparison: Group 1, which underwent the new method, and Group 2, which underwent the conventional method. The statistical analysis was calculated using the Mann–Whitney U test.