Dietary Sodium Intake and Arterial Blood Pressure
Dietary Sodium Intake and Arterial Blood Pressure
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DOI：
10.1053/j.jrn.2008.10.006
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发表时间：
2009-01-01
影响因子：
3.2
通讯作者：
Dumler, Francis
中科院分区：
文献类型：
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作者：
Dumler, Francis
我们试图总结最近在饮食钠摄入量和动脉血压领域的主要研究，并讨论以下试验。盐间：随着年龄的增长，钠摄入量与血压升高有关，但与高血压患病率无关。人群研究发现钠摄入量对血压的影响很小（盐摄入量差异为0.9毫米汞柱/10毫摩尔）。Dash：与对照饮食相比，这种饮食显著降低了血压。DASH和50 mmol/d钠摄入量进一步降低。《先锋》：血压与尿钾、钙、镁呈负相关，但与钠排泄无关。基调：心血管事件在常规护理组最高（83%），在减钠加减肥组最低（56%）。荟萃分析：一项对11项长期对照随机试验的系统回顾报告了小幅下降(1。1毫米汞柱)的中位收缩压，而不是舒张压与减少饮食钠摄入量。综上所述，(1)高血压患者限钠可降低血压；(2)减少盐摄入量对血压、死亡率和发病率的长期影响仍有待确定。(C) 2009年由国家肾脏基金会，Inc。版权所有。
We sought to summarize major recent studies in the field of dietary sodium intake and arterial blood pressure, and discuss the following trials.Intersalt: Sodium intake correlates with the rise in blood pressure with age, but not with the prevalence of hypertension. The population study identified a minimal impact of sodium intake on blood pressure (0.9 mm Hg/10 mmol difference in salt intake).Dash: This diet induced significant reductions in blood pressure compared with the control diet. Further decreases were observed with DASH and a 50 mmol/day sodium intake.Vanguard: Blood pressure was inversely related to urinary potassium, calcium and magnesium but not to sodium excretion.Tone: Cardiovascular events were highest in the usual care group (83%) and lowest in the sodium reduction-plus-weight loss group (56%).Meta-Analysis: A systematic review of 11 long-term controlled randomized trials reported a small decrease (1. 1 mm Hg) in median systolic but not diastolic blood pressure with a reduced dietary sodium intake.In conclusion, (1) sodium restriction in hypertensive patients reduces blood pressure, and (2) the long-term impact of reduced salt intake on blood pressure, mortality, and morbidity remains to be defined. (C) 2009 by the National Kidney Foundation, Inc. All rights reserved.