Characteristics of corneal topographic and pachymetric patterns in patients with pellucid marginal corneal degeneration
Characteristics of corneal topographic and pachymetric patterns in patients with pellucid marginal corneal degeneration
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DOI：
10.1007/s10384-013-0291-3
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发表时间：
2014-03-01
影响因子：
2.4
通讯作者：
Nishida, Kohji
中科院分区：
文献类型：
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作者：
Fuchihata, Mutsumi;Maeda, Naoyuki;Nishida, Kohji
为确定透明边缘角膜变性（PMD）患者的角膜形态特征，并与圆锥角膜和正常人的角膜形态特征进行比较，对33例PMD患者的49只眼进行了回顾性横断面病例系列研究，对51例51眼圆锥角膜患者和53例53眼正常人角膜进行了检查和比较。对于所有的眼睛，我们获得了地形图的轴功率图，前，后高程图和厚度测量图使用旋转Scheimpflug相机。在PMD患者中，最常见的轴向屈光力图型为蟹爪型（78%），其次为下陡型（18%）。圆锥角膜以下陡型最常见（67%）.在PMD和圆锥角膜患者中，两个表面的高度图中最常见的模式是不对称岛。尽管角膜厚度测量图上的偏心模式（包括偏心椭圆形（27%）和偏心圆形（20%））是PMD眼所特有的，但其发生率相对较低，PMD眼和圆锥角膜的角膜地形图和角膜厚度测量图的相似性提示它们可能是同一疾病不同表型的延续。
To determine the characteristics of the shape of the cornea in patients with pellucid marginal corneal degeneration (PMD) and to compare these characteristics to those of eyes with keratoconus and eyes of normal subjects.This was a retrospective, cross-sectional case-series in which 49 eyes of 33 patients with PMD, 51 eyes of 51 patients with keratoconus and 53 eyes of 53 subjects with normal corneas (controls) were examined and compared. For all eyes, we obtained the topographic patterns of the axial power maps, anterior and posterior elevation maps and pachymetric maps using a rotating Scheimpflug camera. The eyes were classified into the respective patterns by visual inspection of these maps.In eyes with PMD, the most common axial power map pattern was the crab claw pattern (78 %) followed by the inferior steepening pattern (18 %). In eyes with keratoconus, the most common pattern was the inferior steepening pattern (67 %). The most common pattern in the elevation maps for both surfaces was the asymmetric island in eyes with PMD and keratoconus. Although the decentered pattern, including the decentered oval (27 %) and decentered round (20 %) pattern, on pachymetric map was specific to eyes with PMD, the incidence of these patterns was relatively low.The similarity in the topographic and pachymetric patterns in eyes with PMD and keratoconus suggests that they may be a continuity of the same disorder with different phenotypes.