The relationship between keloid growth pattern and stretching tension - Visual analysis using the finite element method
The relationship between keloid growth pattern and stretching tension - Visual analysis using the finite element method
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DOI：
10.1097/sap.0b013e3181238dd7
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发表时间：
2008-04-01
影响因子：
1.5
通讯作者：
Hyakusoku, Hiko
中科院分区：
文献类型：
--
作者：
Akaishi, Satoshi;Akimoto, Masataka;Hyakusoku, Hiko
背景：瘢痕疙瘩像恶性肿瘤一样水平生长和扩散，原因尚不清楚。然而，拉伸张力显然与瘢痕疙瘩的产生有关，因为瘢痕疙瘩往往发生在高张力部位，如胸部前部和肩胛骨区。因此，我们使用可视化有限元研究分析了瘢痕疙瘩生长模式和拉伸张力之间的关系。材料与方法：使用DISCUS软件复制瘢痕疙瘩、正常皮肤和脂肪结构。轮廓转移到ADINA分析软件中重建和网格体积。结果：(1)拉伸后的瘢痕疙瘩在边缘处出现高张力，而不是整个区域。(2)瘢痕疙瘩中心是低张力区域，这有助于解释通常发生在瘢痕疙瘩中心区域的愈合。(3)瘢痕疙瘩沿着被拉的方向扩张。(4)随着拉伸张力的增加，出现“蟹爪”状侵入。(5)瘢痕疙瘩周围的皮肤僵硬与张力大大增加有关。(6)脂肪硬度和厚度对拉伸量没有影响。(7)与皮下硬组织的粘连大大增加了瘢痕疙瘩的张力。结论：这些拉伸结果对瘢痕疙瘩在不同条件下的形成有了更深入的了解。我们的结果表明，拉伸张力是与瘢痕疙瘩生长相关的重要条件。
Background: Keloids grow and spread horizontally, like malignant tumors, for reasons that remain unknown. Yet, stretching tension is clearly associated with keloid generation, as keloids tend to occur on high tension sites such as the anterior chest and scapular region. Thus, we analyzed the relationship between keloid growth patterns and stretching tension using a visualized finite element study.Materials and Methods: Keloids, normal skin, and fat structures were reproduced using DISCUS software. The contours were transferred to ADINA analytical software to rebuild and mesh volumes.Results: (1) High tension was observed at the edges, and not in the entire region, of stretched keloids. (2) Keloid centers were regions of low tension, which helps to explain the healing that generally occurs in the central regions of keloids. (3) Expansion of a keloid occurred in the direction in which it was pulled. (4) The "crab's claw"-shaped invasion occur-red in response to increased stretching tension. (5) Skin stiffness in the circumference of a keloid was associated with greatly increased tension. (6) Fat hardness and thickness did not influence the amount of tension. (7) Adhesion with subcutaneous hard tissue greatly increased the tension in the keloid.Conclusion: These stretching results have advanced understanding of keloid formation under various conditions. Our results suggest that stretching tension is an important condition associated with keloid growth.