A controlled study of Methylphenidate in the treatment of Attention Deficit Disorder, Residual Type, in Adults
A controlled study of Methylphenidate in the treatment of Attention Deficit Disorder, Residual Type, in Adults
复制标题
哌醋甲酯治疗成人残留型注意力缺陷障碍的对照研究
DOI：
10.1177/0975156419850118
复制
发表时间：
1985
影响因子：
2.8
通讯作者：
M. Ward
中科院分区：
文献类型：
--
作者：
P. Wender;F. Reimherr;D. Wood;M. Ward
37例符合犹他州残留型注意缺陷障碍标准的成年患者进入哌甲酯和安慰剂的双盲交叉试验。21名（57%）接受哌甲酯治疗的患者和4名（11%）接受安慰剂治疗的患者出现中度至显著的治疗反应，这在统计学和临床上都有非常显著的差异。有反应的患者在以下方面表现出显着的改善：注意力困难，运动过度活跃，情感不稳定和冲动。注意力缺陷障碍，残留型，应考虑患者的突出投诉冲动，坐立不安，情绪不稳定，脾气暴躁，不患有精神分裂症或重大情绪障碍，没有症状的典型或边缘型人格障碍。
Thirty-seven adult patients meeting the Utah criteria for attention deficit disorder, residual type, were entered into a double-blind crossover trial of methylphenidate and placebo. A moderate-to-marked therapeutic response occurred in 21 (57%) of the patients while receiving methylphenidate and in four (11%) while receiving placebo, a highly significant difference statistically and clinically. The responding patients showed significant improvement in the following areas: attentional difficulty, motor overactivity, affective lability, and impulsivity. The diagnosis of attention deficit disorder, residual type, should be considered in patients with prominent complaints of impulsivity, restlessness, emotional lability, and hot temper who do not suffer from schizophrenia or major mood disorder and do not have symptoms of schizotypal or borderline personality disorders.