Short and long term prognosis of patients with myocardial infarction Hungarian Myocardial Infarction Registry

Short and long term prognosis of patients with myocardial infarction Hungarian Myocardial Infarction Registry
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DOI:
10.1556/oh.2013.29679
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发表时间:
2013-08-01
期刊:
影响因子:
0.6
通讯作者:
Dinya Elek
Dinya Elek
中科院分区:
医学4区
文献类型:
--
作者:
Janosi Andras;Ofner Peter;Dinya Elek

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导言:匈牙利急性心肌梗死患者的死亡率数据不完整。目的:作者的目的是分析在匈牙利心肌梗死登记处登记的8582例心肌梗死患者(4981例ST段抬高型心肌梗死)的数据,以确定医院、30天和1年死亡率。为了评估心肌梗死的院前死亡率,在布达佩斯的五个区登记了所有心肌梗死和猝死。方法:采用多因素Logistic回归分析确定死亡危险因素,并用c统计量对模型进行检验。结果:ST段抬高心肌梗死患者的住院、30天和1年死亡率分别为3.7%、9.5%和16.5%。在无ST段抬高心肌梗死的患者中,这些数字分别为4%、9.8%和21.7%。无ST段抬高者1年病死率高于ST段抬高者,差异有统计学意义。年龄、Killip分级、糖尿病、卒中史和心肌梗死是死亡的独立预测因素。冠状动脉介入治疗明显改善了心肌梗死患者的预后。结论:院前死亡率相当高,72.5%的30天死亡发生在入院前。
Introduction: Mortality data of patients with acute myocardial infarction are incomplete in Hungary. Aim: The aim of the authors was to analyse the data of 8582 myocardial infarction patients (4981 with ST-elevation myocardial infarction) registered in the Hungarian Myocardial Infarction Register in order to define the hospital, 30-day, and 1-year mortality. To evaluate the prehospital mortality of myocardial infarction, all myocardial infarction and sudden death were registered in five districts of Budapest. Method: Multivariate logistic regression was performed to define risk factors of mortality and the model were assessed using c statistics. Results: The hospital, 30-day and 1-year mortality of patients with ST elevation myocardial infarction were 3.7%, 9.5% and 16.5%, respectively. In patients without ST elevation myocardial infarction these figures were 4%, 9.8% and 21.7%, respectively. The 1-year mortality of patients without ST elevation was higher than those of with ST elevation and the difference was statistically significant. Age, Killip class, diabetes mellitus, history of stroke and myocardial infarction were independent predictors of death. Coronary intervention improved the prognosis of patients with myocardial infarction significantly. Conclusions: The rate of pre-hospital mortality was considerably high; 72.5% of 30 day mortality occurred before admission to hospital.