Inhibition of oscillation in a neuronal network model for tinnitus management by sound therapy
Inhibition of oscillation in a neuronal network model for tinnitus management by sound therapy
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发表时间：
2010-08
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通讯作者：
H. Nagashino;Y. Kinouchi;A. Danesh;A. Pandya
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作者：
H. Nagashino;Y. Kinouchi;A. Danesh;A. Pandya
耳鸣是在没有任何外部声音的情况下听到耳朵或头部的声音的状态。耳鸣的治疗方法有很多，声疗是目前提出的治疗方法之一。为了从神经工程学的角度探讨耳鸣产生的机制和声音治疗的临床效果，我们利用神经振荡器或简化霍奇金-赫胥黎方程描述的模型神经元，提出了具有可塑性和抑制性反馈的计算模型。在本文中，描述了神经网络模型的改进，在临床结果的再现，人的听觉系统暂时停止耳鸣的感觉后，声音治疗。
Tinnitus is a state in which one hears sounds in the ear or head without any external sound. There are many therapeutic approaches for tinnitus and sound therapy is one of the techniques for its treatment that have been proposed. In order to investigate mechanisms of tinnitus generation and the clinical effects of sound therapy from the viewpoint of neural engineering, we have proposed computational models with plasticity and inhibitory feedback using a neural oscillator or model neurons described by simplified Hodgkin-Huxley equations. In the present paper, the improvement of the neuronal network model is described in the reproduction of the clinical results that human auditory system temporarily halts perception of tinnitus following sound therapy.