The prognostic significance of early treatment response in pediatric relapsed acute myeloid leukemia: results of the international study Relapsed AML 2001/01
The prognostic significance of early treatment response in pediatric relapsed acute myeloid leukemia: results of the international study Relapsed AML 2001/01
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DOI：
10.3324/haematol.2014.104182
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发表时间：
2014-09-01
期刊：
影响因子：
10.1
通讯作者：
Kaspers, Gertjan L.
中科院分区：
文献类型：
--
作者：
Creutzig, Ursula;Zimmermann, Martin;Kaspers, Gertjan L.
复发的小儿急性髓性白血病早期治疗反应的预后意义尚未报道。为了确定一个早期和易于应用的预后因素，允许随后的治疗修改，我们在国际复发- aml2001 /01试验的338例患者首次再诱导后的第15天和第28天通过形态学评估骨髓中的白血病细胞计数。第15天和第28天的状态均为良好(
The prognostic significance of early response to treatment has not been reported in relapsed pediatric acute myeloid leukemia. In order to identify an early and easily applicable prognostic factor allowing subsequent treatment modifications, we assessed leukemic blast counts in the bone marrow by morphology on days 15 and 28 after first reinduction in 338 patients of the international Relapsed-AML2001/01 trial. Both day 15 and day 28 status was classified as good (