ACT: the Artemis comparison tool

ACT: the Artemis comparison tool
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DOI:
10.1093/bioinformatics/bti553
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发表时间:
2005-08-15
期刊:
影响因子:
5.8
通讯作者:
Parkhill, J
Parkhill, J
中科院分区:
生物学3区
文献类型:
--
作者:
Carver, TJ;Rutherford, KM;Parkhill, J

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阿尔忒弥斯比较工具(ACT)能够对完整基因组序列及相关注释之间的比较进行交互式可视化展示。比较数据可由几种不同的程序生成;基因组DNA序列之间的BLASTN、TBLASTX或Mummer比较,或者蛋白质组之间通过相互FASTA比较生成的直系同源物表。从整个基因组到碱基对差异的任何层面上,都有可能识别出相似区域、插入和重排。ACT使用阿尔忒弥斯组件来显示序列,因此继承了强大的搜索和分析工具。ACT是阿尔忒弥斯发布软件的一部分,同样是开源的,用Java编写,可在任何支持Java的平台上运行,包括UNIX、Macintosh和Windows。
The Artemis Comparison Tool (ACT) allows an interactive visualisation of comparisons between complete genome sequences and associated annotations. The comparison data can be generated with several different programs; BLASTN, TBLASTX or Mummer comparisons between genomic DNA sequences, or orthologue tables generated by reciprocal FASTA comparison between protein sets. It is possible to identify regions of similarity, insertions and rearrangements at any level from the whole genome to base-pair differences. ACT uses Artemis components to display the sequences and so inherits powerful searching and analysis tools. ACT is part of the Artemis distribution and is similarly open source, written in Java and can run on any Java enabled platform, including UNIX, Macintosh and Windows.