Deep-probe metal-clad waveguide biosensors
Deep-probe metal-clad waveguide biosensors
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DOI：
10.1016/j.bios.2006.05.025
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发表时间：
2007-02-15
影响因子：
12.6
通讯作者：
Pedersen, H. C.
中科院分区：
文献类型：
--
作者：
Skivesen, N.;Horvath, R.;Pedersen, H. C.
对两种类型的金属包层波导生物传感器，即所谓的浸入型和峰值型进行了分析和测试。它们的性能以著名的表面等离子共振生物传感器为基准，显示出对于厚度超过 150-200 nm 的吸附层的改进的探针特性。浸入式金属包层波导传感器被证明是表面等离子共振生物传感器的最佳全面替代品。两种金属包层波导均经过细胞检测实验测试，显示检测范围为 8-9 个细胞/mm(2)。 (c) 2006 Elsevier B.V. 保留所有权利。
Two types of metal-clad waveguide biosensors, so-called dip-type and peak-type, are analyzed and tested. Their performances are benchmarked against the well-known surface-plasmon resonance biosensor, showing improved probe characteristics for adlayer thicknesses above 150-200 nm. The dip-type metal-clad waveguide sensor is shown to be the best all-round alternative to the surface-plasmon resonance biosensor. Both metal-clad waveguides are tested experimentally for cell detection, showing a detection linut of 8-9 cells/mm(2). (c) 2006 Elsevier B.V. All rights reserved.