Movement analysis by accelerometry of newborns and infants for the early detection of movement disorders due to infantile cerebral palsy
Movement analysis by accelerometry of newborns and infants for the early detection of movement disorders due to infantile cerebral palsy
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DOI：
10.1007/s11517-010-0624-z
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发表时间：
2010-08-01
影响因子：
3.2
通讯作者：
Disselhorst-Klug, Catherine
中科院分区：
文献类型：
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作者：
Heinze, Franziska;Hesels, Katharina;Disselhorst-Klug, Catherine
到目前为止，已开发的早期检测新生儿脑性瘫痪(ICP)运动障碍的诊断策略并不容易应用于临床。它们要么难以获得，要么过于昂贵，无法在儿科诊所建立，而且没有足够的实用性，无法融入日常生活。因此，这项研究的目的是开发一种方法，使其能够客观诊断由于颅内压而导致的新生儿运动障碍。它应适用于儿科办公室，并应易于融入日常工作。为了实现这一点，开发了一种基于加速度计的简单易用和低成本的系统来评估新生儿的运动。然后，实现了一个基于决策树算法的分类器来区分健康数据和病理数据，以提出最可能的诊断。该方法在19名健康受试者和4名患病受试者的临床研究中得到了验证，这些受试者在出生后1个月、3个月和5个月(校正年龄)进行了评估。对于所有评估的测量，所开发的方法的总体检测率达到88%至92%。该方法简单易行，适用于新生儿妊娠期肝内胆汁淤积症的客观诊断，并可在儿科办公室建立，用于日常工作。
So far, developed diagnostic strategies for the early detection of movement disorders due to infantile cerebral palsy (ICP) in newborns are not easily applicable in clinical settings. They are either difficult to acquire or they are too expensive to be established in pediatric clinics and are not sufficiently usable to be integrated into daily routine. The aim of this study therefore was to develop a methodology that allows the objective diagnosis of developing movement disorders in newborns due to ICP. It should be applicable to pediatric offices and should easily integrate in daily routine. To achieve this, a simple to use and low-cost system based on accelerometers was developed to evaluate the newborn's movement. Afterward, a classificator based on a decision tree algorithm was implemented to differentiate between healthy and pathological data in order to propose the most likely diagnosis. The developed methodology was validated in a clinical study with 19 healthy and 4 affected subjects that were evaluated at the first, third and fifths month after birth (corrected age). The overall detection rate of the developed methodology reached between 88 and 92% for all evaluated measurements. The developed methodology is simple to use, therefore is applicable for the objective diagnosis of developing movement disorders in newborns due to ICP and can be established in pediatric offices for use in daily routine.