Positive ion electrospray ionization mass spectrometry of oligonucleotides
Positive ion electrospray ionization mass spectrometry of oligonucleotides
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DOI：
10.1016/s1044-0305(96)00202-4
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发表时间：
1997-01-01
影响因子：
3.2
通讯作者：
Loo, JA
中科院分区：
文献类型：
--
作者：
SannesLowery, KA;Mack, DP;Loo, JA
已获得脱氧核糖核酸（DNA）和核糖核酸（RNA）的正离子电喷雾电离质谱，包括转移RNA（77聚体，类似于25 kDa）。在几种不同的溶液条件下，测定了DNA和RNA分子的电荷态分布。据推测，多电荷正离子的产生是由含氮碱基和寡核苷酸之间的复合物的气相解离引起的。(C)1997年美国质谱学会
Positive ion electrospray ionization mass spectra have been obtained of deoxyribonucleic acids (DNA) and ribonucleic acids (RNA), including transfer RNAs (77-mer, similar to 25 kDa). For several different solution conditions, the charge state distributions of DNA and RNA molecules were determined. It is postulated that the production of the multiply charged positive ions results from gas phase dissociation of complexes between nitrogen-containing bases and oligonucleotides. (C) 1997 American Society for Mass Spectrometry