Unified model of dynamic forced barrier crossing in single molecules
Unified model of dynamic forced barrier crossing in single molecules
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DOI：
10.1103/physrevlett.100.138302
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发表时间：
2008-04-04
影响因子：
8.6
通讯作者：
Friddle, Raymond W.
中科院分区：
文献类型：
--
作者：
Friddle, Raymond W.
在负荷增加的情况下，热激活势垒穿越可以揭示在一定负荷范围内重复的动力学速率常数和能量势垒参数。在这里，我们导出了所有相关加载率的平均逃逸力模型-完整的力谱。两个众所周知的近似作为极限情况出现，其中一个证实了单势垒谱在慢加载极限下收敛于现象学描述的预测。
Thermally activated barrier crossing in the presence of an increasing load can reveal kinetic rate constants and energy barrier parameters when repeated over a range of loading rates. Here we derive a model of the mean escape force for all relevant loading rates-the complete force spectrum. Two well-known approximations emerge as limiting cases, one of which confirms predictions that single-barrier spectra should converge to a phenomenological description in the slow loading limit.