SCREENING STRATEGY FOR POPULATION STUDIES IN SYSTEMIC LUPUS-ERYTHEMATOSUS - SERIES DESIGN
SCREENING STRATEGY FOR POPULATION STUDIES IN SYSTEMIC LUPUS-ERYTHEMATOSUS - SERIES DESIGN
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DOI：
10.1002/art.1780230204
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发表时间：
1980-01-01
影响因子：
--
通讯作者：
SCHUR, PH
中科院分区：
文献类型：
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作者：
LIANG, MH;MEENAN, RF;SCHUR, PH
使用2个系列测试的调查设计大大提高了筛选的效率。本研究旨在确定系统性红斑狼疮（SLE）患者筛查问卷的敏感性、特异性和预测价值。一个系列的设计，其中使用这份问卷，其次是抗核抗体测试，增加了阳性筛查结果的预测值5至10倍，这取决于疾病流行的估计。一项系列设计的实证研究发现了2例SLE新病例，使用基于公认标准的问卷调查在理论上是合理和实用的。这种方法应被证明是有用的SLE的人群调查，以避免以往的流行病学研究的采样和检测偏倚。
A survey design which uses 2 tests in series greatly increases the efficiency of screening. A study to ascertain the sensitivity, specificity and predictive value of a screening questionnaire for systemic lupus erythematosus (SLE) patients is conducted. A series design in which this questionnaire is used, followed by an antinuclear antibody test, increases the predictive value of a positive screening result by 5- to 10-fold, depending on estimates of disease prevalence. An empirical study of the series design identified 2 new cases of SLE, the use of a questionnaire based on accepted criteria is theoretically sound and practical. This approach should prove useful for population surveys of SLE to avoid the sampling and detection biases of previous epidemiologic studies.