Mulberry anthracnose antagonists (iturins) produced by Bacillus amyloliquefaciens RC-2
Mulberry anthracnose antagonists (iturins) produced by Bacillus amyloliquefaciens RC-2
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DOI：
10.1016/s0031-9422(02)00365-5
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发表时间：
2002-11-01
期刊：
影响因子：
3.8
通讯作者：
Fujii, Y
中科院分区：
文献类型：
--
作者：
Hiradate, S;Yoshida, S;Fujii, Y
解淀粉芽孢杆菌菌株RC-2产生分泌到培养滤液中的七种抗真菌化合物（1-7）。这些化合物对桑葚炭疽病的发生有抑制作用。通过NMR和FAB-MS的化学结构分析表明，所有这些化合物均为伊枯草菌素（具有以下序列的环肽：L-Asn --> D-Tyr --> D-Asn --> L-Gln --> L-Pro --> D-Asn --> L-Ser --> D-β-氨基酸-->），并且化合物1-6分别与伊枯草菌素A-2-A-7相同。化合物7（iturin A-8）是一个新的iturin，其在分子中的β-氨基酸中具有-（CH 2）（10）CH（CH 3）CH 2CH 3基团作为侧链。(C)2002爱思唯尔科技有限公司版权所有。
Bacillus amyloliquefaciens strain RC-2 produced seven antifungal compounds (1-7) secreted into the culture filtrate. These compounds inhibited the development of mulberry anthracnose caused by the fungus, Colletotrichum dematium. Chemical structural analyses by NMR and FAB-MS revealed that all these compounds were iturins (cyclic peptides with the following sequence: L-Asn --> D-Tyr --> D-Asn --> L-Gln --> L-Pro --> D-Asn --> L-Ser --> D-beta-amino acid -->) and compounds 1-6 are identical to iturins A-2-A-7, respectively. Compound 7 (iturin A-8) is a new iturin, which has a -(CH2)(10)CH(CH3)CH2CH3 group as a side chain in the beta-amino acid in the molecule. (C) 2002 Elsevier Science Ltd. All rights reserved.