Frequencies of ABO, MNSs, and Duffy phenotypes among blood donors and malaria patients from four Brazilian Amazon areas
Frequencies of ABO, MNSs, and Duffy phenotypes among blood donors and malaria patients from four Brazilian Amazon areas
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DOI：
10.1353/hub.2006.0034
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发表时间：
2006-04-01
期刊：
影响因子：
--
通讯作者：
Dantas Machado, Ricardo Luiz
中科院分区：
文献类型：
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作者：
Cavasini, Carlos Eugenio;De Mattos, Luiz Carlos;Dantas Machado, Ricardo Luiz
我们比较了来自巴西四个亚马逊地区的417名献血者和309名疟疾患者的ABO、MNSs和Duffy的血清学表型频率。我们的研究结果表明，在所有研究地区ABO表型与疟疾感染之间没有相关性。我们在三个地区观察到S + S +、S + S -和S - S +表型与疟疾感染的显著相关性。一些达菲表型在不同地区的捐赠者和疟疾患者之间显示出显著的相关性。这些数据是对确定不同宿主对疟疾易感性的又一贡献。
We compared the serological phenotypic frequencies of ABO, MNSs, and Duffy in 417 blood donors and 309 malaria patients from four Brazilian Amazon areas. Our results suggest no correlation between ABO phenotype and malaria infection in all areas studied. We observed significant correlation between the S + s +, S + s-, and S - s + phenotypes and malaria infection in three areas. Some of the Duffy phenotypes showed significant correlation between donors and malaria patients in different areas. These data are an additional contribution to the establishment of differential host susceptibility to malaria.