Branch retinal vein occlusion-associated subretinal hemorrhage

Branch retinal vein occlusion-associated subretinal hemorrhage
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DOI:
10.1007/s10384-013-0236-x
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发表时间:
2013-05-01
影响因子:
2.4
通讯作者:
Yoshimura, Nagahisa
Yoshimura, Nagahisa
中科院分区:
医学4区
文献类型:
--
作者:
Muraoka, Yuki;Tsujikawa, Akitaka;Yoshimura, Nagahisa

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为探讨视网膜分支静脉阻塞(BRVO)患者视网膜下出血(SRH)的病理形态学特征及其与视力预后的关系,对42例(42眼)累及中心凹的BRVO患者进行回顾性分析。用光谱域光学相干断层扫描(SD-OCT)检查视网膜结构改变,35眼在SD-OCT上发现中心凹浆液性视网膜脱离,其中18眼伴有中心凹SRH。中心凹SRH的初始检测与初始视力(VA)无相关性,但与最终视力较差相关(r = 0.361,P = 0.019)。我们的患者被分为两组的初始检测中心凹的SRH,初始VA是这两组之间没有差异。在最后检查时,SRH阳性组的视网膜中央凹感光层损伤长度明显长于SRH阴性组SRH阳性组的最终视力明显差于SRH阴性组(P = 0.004中心凹SRH在BRVO中并不少见,并且可能导致中心凹感光层的后续损伤,从而导致视觉功能差。
To study the pathomorphology of subretinal hemorrhage (SRH) seen in eyes with branch retinal vein occlusion (BRVO) and its association with visual prognosis.We retrospectively reviewed 42 consecutive patients (42 eyes) with BRVO that affected the fovea. Retinal structural changes were examined by spectral domain optical coherence tomography (SD-OCT).On SD-OCT sections, serous retinal detachment was seen at the fovea in 35 eyes, 18 of which accompanied foveal SRH. While initial detection of foveal SRH had no correlation with initial visual acuity (VA), it was correlated with poorer final VA (r = 0.361, P = 0.019). Our patients were classified into two groups by the initial detection of foveal SRH, and initial VA was not different between these two groups. At the final examination, damaged lengths in the foveal photoreceptor layer were significantly longer in the SRH-positive group than those in the SRH-negative group (P = 0.004), and final VA in the SRH-positive group was significantly worse than that in the SRH-negative group (P = 0.019).Foveal SRH is not an uncommon feature in BRVO and may cause subsequent damage to the foveal photoreceptor layer, resulting in poor visual function.