RESTORATION OF BAROREFLEX CONTROL OF HEART-RATE DURING RECOVERY FROM ANESTHESIA
RESTORATION OF BAROREFLEX CONTROL OF HEART-RATE DURING RECOVERY FROM ANESTHESIA
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DOI：
10.1093/bja/58.4.415
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发表时间：
1986-04-01
影响因子：
9.8
通讯作者：
SPELINA, KR
中科院分区：
文献类型：
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作者：
CARTER, JA;CLARKE, TNS;SPELINA, KR
本文观察了21例患者应用氟烷或甲氧己酮补充67%氧化亚氮对压力感受性反射心率控制的影响。任何一种药物的稳定麻醉均可使压力感受性反射敏感性降低50%以上。反射的设定点也被两种药物改变，但方向相反。注射氟烷会导致较低动脉压的心率减慢，而输注甲氧己酮则会导致较低动脉压时较快的心率。在麻醉恢复期间，压力反射敏感度迅速恢复到正常，这是在患者苏醒之前实现的，两组之间没有差异。在恢复期，反射被迅速且重复地重置。
The effects on baroreflex control of heart rate of halothane or methohexitone used to supplement 67% nitrous oxide in oxygen have been studied in 21 patients. Stable anaesthesia with either agent caused depression of baroreflex sensitivity by more than 50%. The set point of the reflex was also changed by both agents, but in opposite directions. Halothane administration resulted in slower heart rates of lower arterial pressures, whereas the infusion of methohexitone caused faster heart rates at lower arterial pressure. During recovery from anesthesia, there was a rapid return of baroreflex sensitivity to normal and this was achieved before the patients regained consciousness, with no difference between the two groups. The reflex was reset rapidly and repeatedly during the recovery phase.