A comprehensive review of Asherman's syndrome: causes, symptoms and treatment options
A comprehensive review of Asherman's syndrome: causes, symptoms and treatment options
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DOI：
10.1097/gco.0000000000000378
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发表时间：
2017-08-01
影响因子：
2.1
通讯作者：
Morris, Stephanie
中科院分区：
文献类型：
--
作者：
Salazar, Christina A.;Isaacson, Keith;Morris, Stephanie
子宫粘连，也被称为阿什曼综合征，可对生殖结果和妇科症状产生影响。了解宫内粘连的原因和常见的临床表现将提高对这种情况的认识，并指导患者进行适当的治疗。手术治疗提供了良好的生育结果，并经常成功地恢复月经。宫腔镜下粘连溶解的外科治疗是治疗的金标准，采用办公室为基础的方法有几个优点。预防粘连重建仍然具有挑战性，没有一种预防复发的方法显示出优越性。使用子宫内膜干细胞/祖细胞的细胞疗法有望在未来用于再生不足的子宫内膜。提高对提示宫内粘连症症状的认识，以及对常见病因和既往事件的认识，对早期诊断、患者咨询和治疗至关重要。视频abstracthttp: / / links.lww.com/COOG/A36。
Purpose of reviewIntrauterine adhesions, also known as Asherman's syndrome, can have an impact on both reproductive outcomes and gynaecologic symptoms. Understanding the cause of intrauterine adhesions and the common clinical presentation will increase awareness of the condition and guide the patient to appropriate therapy. Surgical management offers favourable fertility outcomes and is often successful in restoring menstruation.Recent findingsSurgical management with hysteroscopic lysis of adhesions is the gold standard for treatment and adopting an office-based approach offers several advantages. Prevention of reformation of adhesions remains challenging and no single method for preventing recurrence has shown superiority. Cell-based therapies using endometrial stem/progenitor cells hold promise for future use in regenerating inadequate endometrium.SummaryIncreased awareness of the symptoms suggestive of intrauterine adhesive disease, as well as recognition of common causes and preceding events, is crucial for early diagnosis, patient counselling and treatment.Video abstracthttp://links.lww.com/COOG/A36.