Lateralization of dementia of depression in stroke patients.
Lateralization of dementia of depression in stroke patients.
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中风患者抑郁症痴呆的偏侧化。
DOI：
10.1176/ajp.146.5.627
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发表时间：
1989
期刊：
影响因子：
--
通讯作者：
Price,TR
中科院分区：
文献类型：
--
作者：
Bolla-Wilson,K;Robinson,RG;Starkstein,SE;Boston,J;Price,TR
在一组左半球受损的中风患者中，重度抑郁症患者在神经心理学测试的九个认知领域中的四个领域的表现明显低于非抑郁症患者。在右脑卒中患者中，重度抑郁症患者在九个认知领域中的任何一个方面的表现都不低于非抑郁症患者。抑郁症对左、右半球病变组认知表现的不同影响不能用人口统计学变量、神经症状、病变位置或病变大小来解释。中风后重度抑郁症似乎会产生认知能力下降或抑郁症痴呆，这取决于病变的侧边性。
In a group of stroke patients with left-hemisphere lesions, those with major depression performed significantly below nondepressed patients on four of nine cognitive domains examined with a neuropsychological test battery. Among patients with right-hemisphere stroke, those with major depression did not perform below nondepressed patients on any of the nine cognitive domains. The differential effect of depression on cognitive performance between left-and right-hemisphere lesion groups could not be accounted for by demographic variables, neurological symptoms, lesion location, or lesion size. Poststroke major depression appeared to produce a decline in cognitive performance or dementia of depression that depended on the laterality of the lesion.