Best Practice No 169
Best Practice No 169
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最佳实践 169 号
DOI：
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发表时间：
2003
影响因子：
3.4
通讯作者：
Dr T R Helliwell
中科院分区：
文献类型：
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作者：
Dr T R Helliwell
这篇最佳实践文章回顾了已发表的有关下咽癌病理学和扩散模式的证据，以及病理特征与预后的相关性。 Medline (1966-2001) 结合头颈部肿瘤和预后进行检索，重点关注下咽部和病理学。其他相关出版物是从这些论文的参考书目以及偶然获得的参考书目中确定的。专门针对下咽鳞状癌的病理学文献相对较少，大多数信息来自于一系列不同部位的头颈癌患者。报告缺乏一致性以及术语的变化使得系列之间的比较变得困难。决定预后的最重要特征是原发癌局部扩散的大小和程度以及区域淋巴结受累的程度。有证据支持在该站点使用头颈癌的最低数据集标准。在下咽部，病因学和生物学方面与亚位点相关的差异可能变得很重要。
This best practice article reviews the published evidence on the pathology and patterns of spread of carcinomas of the hypopharynx, and the relevance of pathological features to prognosis. Medline (1966–2001) was searched using a combination of head and neck neoplasms and prognosis, focusing on hypopharynx and pathology. Other relevant publications were identified from the bibliographies of these papers, and from those obtained opportunistically. There is relatively little pathological literature devoted specifically to squamous carcinomas of the hypopharynx and most information comes from large series of patients with head and neck cancers at a range at sites. Lack of consistency in reporting and shifts in terminology make comparisons between series difficult. The most important features determining prognosis are size and extent of local spread of the primary carcinoma and extent of involvement of regional lymph nodes. There is evidence to support the use of the minimum dataset criteria for head and neck carcinomas at this site. Within the hypopharynx, subsite related differences in aetiology and biology may become important.
头颈鳞状细胞癌中细胞周期蛋白 D1 (PRAD1、CCND1) 和谷胱甘肽-S-转移酶 pi 基因的表达。
影响因子：
3.3
作者：
Gaffey,MJ;Iezzoni,JC;Meredith,SD;Boyd,JC;Stoler,MH;Weiss,LM;Zukerberg,LR;Levine,PA;Arnold,A;Williams,ME
通讯作者：
Williams,ME
影响因子：
158.5
作者：
BRENNAN, JA;MAO, L;SIDRANSKY, D
通讯作者：
SIDRANSKY, D