In vivo 3-Dimensional Kinematics Study of the Healthy Cervical Spine Based on CBCT Combined with 3D-3D Registration Technology
In vivo 3-Dimensional Kinematics Study of the Healthy Cervical Spine Based on CBCT Combined with 3D-3D Registration Technology
复制标题
基于CBCT结合3D-3D配准技术的健康颈椎体内三维运动学研究
作者：
Benyu Tang;Haoqun Yao;Shaobai Wang;Yanlong Zhong;Kai Cao;Zongmiao Wan
首次采用锥形束CT结合3D-3D配准技术，准确描述了在体颈椎节段运动的三维特征。测量结果为颈椎疾病的诊断和治疗提供了必要的生物力学数据支持。研究设计.颈椎生物力学研究。Objective.我们试图使用锥形束计算机断层扫描（CBCT）结合3D-3D配准技术来展示健康志愿者颈椎的三维（3D）椎间运动特征。背景数据总结。之前没有研究使用CBCT结合3D-3D配准技术成功记录颈椎的体内3D椎间六自由度（6-DOF）运动。方法. 20名健康受试者在7个功能位置接受了颈椎（C1-C7）CBCT扫描。根据颈椎CBCT图像建立分段三维椎体模型。然后对不同位置的每个椎体进行3D到3D配准，以计算体内3D节段运动特征。结果在屈伸运动中，C1-C2和C4-C5节段的活动范围（ROM）明显大于其他节段。各节段的平均轴向旋转和侧向弯曲耦合度在0.6° ~ 3.2°之间。在所有方向上的平均耦合平移在0.2和2.1 mm之间。 在轴向旋转过程中，C1-C2的ROM为65.8 ± 5.9°，约占所有轴向旋转的70%。 C1-C2耦合侧弯运动和位移分别为11.4 ± 5.2°和8.3 ± 1.9mm。 侧弯时，C3-C4的ROM显著大于C1-C2、C5-C6和C6-C7。C1-C2轴向旋转耦合为34.4 ± 8.1°，侧向平移耦合为3.8 ± 0.5 mm。 每个颈椎节段的上下和前后平移耦合在0.1和0.6 mm之间。 结论采用CBCT结合3D-3D配准技术，精确测量和记录生理负荷条件下颈椎侧弯、轴向旋转和屈伸活动度。我们的发现可能有助于颈椎疾病的诊断，新的手术技术的发展，以及恢复正常的颈椎节段运动。证据等级：3
Cone beam computed tomography combined with 3D-3D registration technique was used to accurately describe the in vivo three-dimensional features of cervical segmental motion for the first time. The measurement results provide necessary biomechanical data support for the diagnosis and treatment of cervical diseases. Study Design. A cervical biomechanical study. Objective. We sought to demonstrate the three-dimensional (3D) intervertebral motion characteristics of the cervical spine in healthy volunteers using cone beam computed tomography (CBCT) combined with 3D-3D registration technology. Summary of Background Data. No previous studies have used CBCT combined with 3D-3D registration technology to successfully documented in vivo 3D intervertebral six-degrees-of-freedom (6-DOF) motions of the cervical spine. Methods. Twenty healthy subjects underwent cervical (C1–C7) CBCT scans in seven functional positions. Segmented 3D vertebral body models were established according to the cervical CBCT images. A 3D-to-3D registration was then performed for each vertebral body in the different positions to calculate the 3D segmental motion characteristics in vivo. Results. During flexion–extension, the range-of-motion (ROM) of C1–C2 and C4–C5 was significantly greater than the other segments. The average coupled axial rotation and lateral bending of each segment were between 0.6° and 3.2°. The average coupling translations in all directions were between 0.2 and 2.1 mm. During axial rotation, the ROM of C1–C2 was 65.8 ± 5.9°, which accounted for approximately 70% of all axial rotation. The motion and displacement of C1–C2 coupled lateral bending were 11.4 ± 5.2° and 8.3 ± 1.9 mm, respectively. During lateral bending, the ROM of C3–C4 was significantly greater than C1–C2, C5–C6, and C6–C7. The coupled axial rotation of C1–C2 was 34.4 ± 8.1°, and the coupled lateral translation was 3.8 ± 0.5 mm. The coupled superoinferior and anteroposterior translation of each cervical segment were between 0.1 and 0.6 mm. Conclusion. CBCT combined with 3D-3D registration was used to accurately measure and record the ROMs of lateral bending, axial rotation, and flexion–extension in cervical vertebrae under physiological-load conditions. Our findings may contribute to the diagnosis of cervical spinal disease, the development of new surgical techniques, and the restoration of normal, cervical segmental movement. Level of Evidence: 3
影响因子：
2.4
作者：
Zhou, Chaochao;Wang, Haiming;Cha, Thomas
通讯作者：
Cha, Thomas