Oxidant-Responsive Induction of the suf Operon, Encoding a Fe-S Assembly System, through Fur and IscR in Escherichia coli
Oxidant-Responsive Induction of the suf Operon, Encoding a Fe-S Assembly System, through Fur and IscR in Escherichia coli
复制标题
DOI：
10.1128/jb.01161-08
复制
发表时间：
2008-12-01
影响因子：
3.2
通讯作者：
Roe, Jung-Hye
中科院分区：
文献类型：
--
作者：
Lee, Kyung-Chang;Yeo, Won-Sik;Roe, Jung-Hye
在大肠杆菌中，过氧化物通过激活剂OxyR和IscR诱导编码Fe-S组装系统的suf操纵子。为了使apo-IscR结合，需要氧化介导的Fur解离。因此，过氧化物响应信号通过OxyR、IscR和Fur转导，以实现该操纵子的氧化敏感性和最大诱导。
The suf operon encoding a Fe-S assembly system is induced by peroxides through activators OxyR and IscR in Escherichia coli. For apo-IscR to bind, oxidation-mediated dissociation of Fur is required. Therefore, a peroxide-responsive signal is transduced through OxyR, IscR, and Fur to achieve oxidation-sensitive and maximal induction of this operon.