MIGRAINE, PHYSICAL HEALTH AND PSYCHIATRIC-DISORDER - A PROSPECTIVE EPIDEMIOLOGIC-STUDY IN YOUNG-ADULTS
MIGRAINE, PHYSICAL HEALTH AND PSYCHIATRIC-DISORDER - A PROSPECTIVE EPIDEMIOLOGIC-STUDY IN YOUNG-ADULTS
复制标题
DOI：
10.1016/0022-3956(93)90009-q
复制
发表时间：
1993-04-01
影响因子：
4.8
通讯作者：
DAVIS, GC
中科院分区：
文献类型：
--
作者：
BRESLAU, N;DAVIS, GC
在一项对1007名年轻人的随机抽样的前瞻性研究中，我们研究了偏头痛与精神障碍、躯体主诉、功能障碍指标和精神卫生服务使用之间的关系。偏头痛病史与严重抑郁症、焦虑症、非法药物使用障碍、尼古丁依赖和自杀企图的终生发病率增加有关。与无偏头痛病史的受试者相比，有偏头痛病史的受试者有更多的躯体症状，更有可能报告缺勤，评估他们的总体健康状况为一般或较差，并使用心理健康服务。基线访谈后14个月收集的随访数据显示，在基线水平有偏头痛病史的受试者在间隔期内首次发生重度抑郁和惊恐障碍的比例显著增加(OR=4，2，95%可信区间(CI)2.0-9.2；惊恐障碍的OR=12.8，95%可信区间4.1~39.8)。在有偏头痛病史的人中，这些精神障碍的风险与他们最近的偏头痛发作无关。这些发现表明，偏头痛、重度抑郁和焦虑之间的联系可能反映了一种共同的倾向。
In a prospective study of a random sample of 1,007 young adults, we examined the association between migraine and psychiatric disorder, physical complaints, indicators of functional impairment, and use of mental health services. A history of migraine was associated with increased lifetime rates of major depression, anxiety disorders, illicit drug use disorders, nicotine dependence, and suicide attempts. Compared with subjects without a history of migraine, those with such a history had significantly more physical symptoms and were more likely to report job absenteeism, assess their general health as fair or poor, and use mental health services.Follow-up data, gathered 14 months after the baseline interview, revealed that subjects with a history of migraine at the baseline had significantly increased rates of first incidence major depression and panic disorder during the interval period (odds ratio (OR) for major depression = 4,2, 95% confidence inter-val (CI) 2.0-9.2; and OR for panic disorder = 12.8, 95% CI 4.1-39.8). The risk for these psychiatric disorders in persons with prior history of migraine was unrelated to the recentness of their migraine attacks. These findings suggest that the link between migraine, major depression and anxiety might reflect a common predisposition.