Biochemistry and biology of the inducible multifunctional transcription factor TFII-I: 10 years later.

Biochemistry and biology of the inducible multifunctional transcription factor TFII-I: 10 years later.
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DOI:
10.1016/j.gene.2011.10.030
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发表时间:
2012-01-15
期刊:
影响因子:
3.5
通讯作者:
Roy AL
Roy AL
中科院分区:
生物学3区
文献类型:
--
作者:
Roy AL

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整整20年前,TFII-I被发现是一种生物化学实体,能够与称为启动子(Inr)的核心启动子元件结合并通过其发挥作用。从那时起,发现了这种信号诱导的多功能因子的几种不同性质。在这里,我更新了TFII-I不断扩展的功能-主要集中在自第一篇综述发表以来的过去十年。
Exactly twenty years ago TFII-I was discovered as a biochemical entity that was able to bind to and function via a core promoter element called the Initiator (Inr). Since then several different properties of this signal-induced multifunctional factor were discovered. Here I update these ever expanding functions of TFII-I--focusing primarily on the last ten years since the first review appeared in this journal.
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