Quantifying continuous-flow dielectrophoretic trapping of cells and micro-particles on micro-electrode array
Quantifying continuous-flow dielectrophoretic trapping of cells and micro-particles on micro-electrode array
复制标题
量化微电极阵列上细胞和微粒的连续流介电泳捕获
DOI：
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发表时间：
2013
影响因子：
2.8
通讯作者：
G. Yossifon
中科院分区：
文献类型：
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作者：
Lichen Rozitsky;A. Fine;Dekel Dado;Shahar Nussbaum;S. Levenberg;G. Yossifon
嵌入在具有强制流动的微通道内的叉指型电极阵列被示出为基于在连续频率范围内测量它们的捕获百分比来实现颗粒和/或细胞的介电泳（DEP）表征。捕获百分比的简化模型，使用对流和DEP力的空间平均，线性相关的有效DEP力（在其正模式）。因此，Clausius-Mossotti因子与实验数据拟合，得到颗粒和/或细胞的有效电特性。此外，在连续频率范围内生成的捕获百分比曲线响应有助于基于差异而不仅仅是交叉频率进行分类和检测。
An interdigitated electrode array embedded within a micro-channel with forced flow is shown to enable dielectrophoretic (DEP) characterization of particles and/or cells based on measurements of their trapping percentage over a continuous frequency range. A simplified model of the trapping percentage, using spatial averaging of the convective and DEP force, linearly correlated it to the effective DEP force (in its positive mode). Thus, the Clausius–Mossotti factor was fitted to the experimental data, yielding effective electrical characteristics of the particles and/or cells. Also, the generated trapping percentage curve response over a continuous range of frequencies facilitates sorting and detection based on differences other than just the cross-over frequencies.
影响因子：
3.4
作者：
Xiao-Bo Wang;Jody V. Vykoukal;Frederick F. Becker;P. Gascoyne
通讯作者：
Xiao-Bo Wang;Jody V. Vykoukal;Frederick F. Becker;P. Gascoyne