Polytetrafluoroethylene-covered stent and coronary artery aneurysms

Polytetrafluoroethylene-covered stent and coronary artery aneurysms
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DOI:
10.1002/ccd.10063
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发表时间:
2002-03-01
影响因子:
2.3
通讯作者:
Colombo, A
Colombo, A
中科院分区:
医学3区
文献类型:
--
作者:
Briguori, C;Sarais, C;Colombo, A

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在接受冠状动脉造影的患者中,通过血管造影检测到的冠状动脉瘤(即冠状动脉段大于正常动脉的1.5倍)的发生率为0.3%-4.9%,并且在介入手术后报告的发生率为2%-10%。治疗适应症和最佳方式仍需确定。一些作者报道了通过聚四氟乙烯(PTFE)覆盖的支架植入术成功治疗冠状动脉瘤,支持了该策略的作用。在我们机构,从1997年9月到1999年12月,植入了8个PTFE覆盖支架,治疗了7名患有冠状动脉瘤的患者。所有动脉瘤均通过 PTFE 覆盖支架成功治疗。在一种情况下,需要额外的 PTFE 支架来完全覆盖动脉瘤。在任何情况下都没有发生支架丢失的情况。未发生院内 MACE。 35 +/- 8 (21-44) 个月时,六名患者没有症状。所有患者均在 10 +/- 6 个月时进行血管造影随访。一名重复经皮冠状动脉介入治疗的患者 (14%) 发生再狭窄。这一初步经验表明,PTFE 覆盖的支架可能有助于治疗冠状动脉瘤。 (C) 2002 Wiley-Liss, Inc.
Angiographically detected coronary aneurysms (i.e., coronary segment greater then 1.5 times the normal artery) have an incidence of 0.3%-4.9% among patients undergoing coronary angiography and have been reported after an intervention procedure with a frequency of 2%-10%. The indication for treatment and the best modality still need to be defined. Some authors reported the successful treatment of coronary aneurysms with the polytetrafluoroethylene (PTFE)-covered stent implantation, supporting the role of this strategy. In our institution, from September 1997 to December 1999 eight PTFE-covered stents were implanted to treat seven coronary aneurysms In seven patients. All aneurysms were successfully treated by the PTFE-covered stent. In one case, there was the necessity of an additional PTFE stent to cover the aneurysm completely. In no case did the loss of stent occur. No in-hospital MACE occurred. At 35 +/- 8 (21-44) months, six patients were symptom-free. Angiographic follow-up was performed in all patients at 10 +/- 6 months. Restenosis occurred in one patient (14%) who had repeat percutaneous coronary interventions. This preliminary experience suggests that PTFE-covered stent may be useful in the treatment of coronary artery aneurysms. (C) 2002 Wiley-Liss, Inc.