Age and Sex Differences in Heart Failure With Preserved Ejection Fraction.
Age and Sex Differences in Heart Failure With Preserved Ejection Fraction.
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DOI：
10.3389/fragi.2022.811436
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发表时间：
2022
影响因子：
--
通讯作者：
Chiao, Ying Ann
中科院分区：
文献类型：
--
作者：
Kobak, Kamil Aleksander;Zarzycka, Weronika;Chiao, Ying Ann
关键词：
Heart failure with preserved ejection fraction (HFpEF) is a multi-organ disorder that represents about 50% of total heart failure (HF) cases and is the most common form of HF in the elderly. Because of its increasing prevalence caused by the aging population, high mortality and morbidity, and very limited therapeutic options, HFpEF is considered as one of the greatest unmet medical needs in cardiovascular medicine. Despite its complex pathophysiology, numerous preclinical models have been established in rodents and in large animals to study HFpEF pathophysiology. Although age and sex differences are well described in HFpEF population, there are knowledge gaps in sex- and age-specific differences in established preclinical models. In this review, we summarize various strategies that have been used to develop HFpEF models and discuss the knowledge gaps in sex and age differences in HFpEF.
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影响因子：
7.8
作者：
Dai DF;Karunadharma PP;Chiao YA;Basisty N;Crispin D;Hsieh EJ;Chen T;Gu H;Djukovic D;Raftery D;Beyer RP;MacCoss MJ;Rabinovitch PS
通讯作者：
Rabinovitch PS
DOI：
10.18632/aging.100881
发表时间：
2016-02
期刊：
Aging
影响因子：
--
作者：
Chiao YA;Kolwicz SC;Basisty N;Gagnidze A;Zhang J;Gu H;Djukovic D;Beyer RP;Raftery D;MacCoss M;Tian R;Rabinovitch PS
通讯作者：
Rabinovitch PS
影响因子：
12.3
作者：
Charles, CJ;Kaaja, RJ;Yandle, TG
通讯作者：
Yandle, TG
影响因子：
10.8
作者：
Chiao, Ying Ann;Ramirez, Trevi A.;Lindsey, Merry L.
通讯作者：
Lindsey, Merry L.
影响因子：
--
作者：
Chirinos, Julio A;Zamani, Payman
通讯作者：
Zamani, Payman