Limited angle tomographic breast imaging: a comparison of parallel beam and pinhole collimation
Limited angle tomographic breast imaging: a comparison of parallel beam and pinhole collimation
复制标题
有限角度断层乳腺成像：平行光束与针孔准直的比较
DOI：
--
复制
发表时间：
1996
期刊：
影响因子：
--
通讯作者：
B. Tsui
中科院分区：
文献类型：
--
作者：
D. Wessell;D. Kadrmas;E. Frey;B. Tsui
临床试验结果表明，使用 Tc-99m 的平行孔 SPECT 闪烁放射成像 (SM) 与平行孔平面 SM 相比，在病变检测方面没有改善。在这项初步调查中，我们阐明了 SPECT SM 的一些独特要求。考虑到这些要求，我们已经开始开发实用的数据采集和重建策略，以减少图像伪影并提高图像质量。在本文中，我们研究了平行孔和针孔 SPECT SM 的有限角轨道。奇异值分解 (SVD) 用于分析与有限角度轨道相关的伪影。然后使用最大似然期望最大化 (ML-EM) 重建来检查衰减补偿对重建图像质量的影响。所有模拟均使用 3D-MCAT 乳房模型进行。这些仿真研究的结果表明，有限角度SPECT SM是可行的，精确重建需要衰减校正，并且针孔SPECT SM在提高图像质量和减少图像伪影方面可能比平行孔SPECT SM具有优势。
Results from clinical trials have suggested no improvement in lesion detection with parallel hole SPECT scintimammography (SM) with Tc-99m over parallel hole planar SM. In this initial investigation, we have elucidated some of the unique requirements of SPECT SM. With these requirements in mind, we have begun to develop practical data acquisition and reconstruction strategies that can reduce image artifacts and improve image quality. In this paper we investigate limited angle orbits for both parallel hole and pinhole SPECT SM. Singular Value Decomposition (SVD) is used to analyze the artifacts associated with the limited angle orbits. Maximum likelihood expectation maximization (ML-EM) reconstructions are then used to examine the effects of attenuation compensation on the quality of the reconstructed image. All simulations are performed using the 3D-MCAT breast phantom. The results of these simulation studies demonstrate that limited angle SPECT SM is feasible, that attenuation correction is needed for accurate reconstructions, and that pinhole SPECT SM may have an advantage over parallel hole SPECT SM in terms of improved image quality and reduced image artifacts.