Ultrasensitive SERS detection of mercury based on the assembled gold nanochains
Ultrasensitive SERS detection of mercury based on the assembled gold nanochains
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DOI：
10.1016/j.bios.2014.08.088
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发表时间：
2015-05-15
影响因子：
12.6
通讯作者：
Xu, Chuanlai
中科院分区：
文献类型：
--
作者：
Xu, Liguang;Yin, Honghong;Xu, Chuanlai
汞离子（Hg2+）通过碱基对之间的T-Hg2+-T相互作用介导单链DNA转化形成双螺旋DNA。通过这种策略，DNA修饰的金纳米粒子（Au NPs）被组装成链，显示出显着的表面增强拉曼散射（SERS）信号。优化条件下，金纳米链长度与汞离子浓度在0.001-0.5 ng mL(-1)范围内成正比，饮用水中的检测限(LOD)低至0.45 pg mL(-1)。凭借超灵敏性和出色的选择性，这种可行且简单的方法有可能成为食品安全和环境应用中汞离子监测的有前途的工具。 (C) 2014 Elsevier B.V. 保留所有权利。
Mercuric ions (Hg2+) mediate the transformation of single-stranded DNA to form double helical DNA by T-Hg2+-T interaction between base pairs. With this strategy, DNA modified gold nanoparticles (Au NPs) were assembled into chains which were displayed remarkable surface-enhanced Raman scattering (SERS) signal. Under optimized conditions, the length of gold nanochains was directly proportional to the mercuric ions concentrations over 0.001-0.5 ng mL(-1) and the limit of detection (LOD) in drinking water was as low as 0.45 pg mL(-1). With ultrasensitivity and excellent selectivity, this feasible and simple method is potentially as a promising tool for monitoring of mercury ions in food safety and environmental applications. (C) 2014 Elsevier B.V. All rights reserved.