EFFECTS OF ANESTHESIA AND SURGERY ON IMMUNE STATUS
EFFECTS OF ANESTHESIA AND SURGERY ON IMMUNE STATUS
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DOI：
10.1093/bja/51.1.37
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发表时间：
1979-01-01
影响因子：
9.8
通讯作者：
WALTON, B
中科院分区：
文献类型：
--
作者：
WALTON, B
麻醉实践的免疫学意义与以下可能性有关：暴露于麻醉和手术，通过抑制各种非特异性抵抗机制和特异性免疫反应，使患者在手术后更容易感染和恶性肿瘤扩散。虽然各种麻醉剂抑制免疫反应，但与应激反应的激素方面的影响相比，这种影响可能是短暂的，并且不太重要。从免疫学的角度来看，更积极的缓解疼痛和焦虑的方法可能是有益的。
The immunological implications of anesthetic practice relate to the possibility that exposure to anesthesia and surgery, by depressing a variety of non-specific resistance mechanisms and specific immune responses, renders patients more liable to infections and the spread of malignancy in the period after operation. Although various anesthetic agents depress immune responses, the effects may be short-lived and of minor importance when compared with the effects of the hormonal aspects of the stress response. A more aggressive approach to relief of pain and anxiety may be beneficial from the immunological point of view.