Diagnostic utility of laser-Doppler vibrometry in conductive hearing loss with normal tympanic membrane
Diagnostic utility of laser-Doppler vibrometry in conductive hearing loss with normal tympanic membrane
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DOI：
10.1097/00129492-200303000-00008
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发表时间：
2003-03-01
影响因子：
2.1
通讯作者：
Merchant, SN
中科院分区：
文献类型：
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作者：
Rosowski, JJ;Mehta, RP;Merchant, SN
假设：假设激光多普勒测振仪测量充气中耳Umbo的传导速度可以区分听小骨中断、砧骨固定和踝关节固定。更广泛地说，我们假设激光多普勒测振仪测量Umbo速度可以提供有关听小骨所针对的阻抗差异如何影响中耳功能的信息。背景：激光多普勒测振仪是探索中耳功能的成熟研究工具。作者希望探讨其作为临床鉴别诊断传导性听力损失原因的工具的潜力。方法：应用激光多普勒测振仪，在鼓膜正常和中耳充气的情况下，研究鼓膜声诱发速度与传导性听力损失的关系。对17只成人耳在探查鼓室切开前的测量结果与手术确定的听力损失原因进行了比较。作者还测量了10名成功接受了小骨窗切除手术的患者的Umbo的运动。结果：正常耳与不同听骨病患耳的Umbo速度有明显的统计学差异。听骨中断和听骨固定的结果也有明显的区别。结论：激光多普勒测振结果与听骨中断患者的测听结果基本一致。结论：激光多普勒测振结果与测听结果的比较可能是一项敏感而有选择性的听小骨病变指标，也是研究中耳功能的有用工具。
Hypothesis: It was hypothesized that laser-Doppler vibrometry measurements of umbo velocity in aerated middle ears with conductive loss can differentiate ossicular interruptions, stapes fixations, and mallear fixations. More generally, we hypothesize that laser-Doppler vibrometry measurements of umbo velocity can give information about how differences in the impedance that the ossicles work against affect middle-ear function.Background: Laser-Doppler vibrometry is a well-established research tool for exploring middle-ear function. The authors wished to investigate its potential as a clinical tool for differential diagnosis of the cause of conductive hearing loss.Methods: Laser-Doppler vibrometry was used to investigate the relationship between the sound-induced velocity of the tympanic membrane at the umbo and the cause of conductive hearing loss when the tympanic membrane was normal and the middle ear was aerated. The results of measurements in 17 adult ears before exploratory tympanotomy were compared with the surgically determined cause of the hearing loss. The authors also measured the motion of the umbo in 10 patients who had undergone successful small-fenestra stapedectomy procedures. In all the studied ears, pure-tone audiograms were measured at the time of laser-Doppler vibrometry testing.Results: There were clear statistical differences between the umbo velocity in normal ears and in ears with different ossicular pathologic conditions. There was also a clear separation of the results between ears with ossicular interruptions and ossicular fixation. The pattern of laser-Doppler vibrometry measurements in poststapedectomy ears approximated the pattern in ears with ossicular interruptions.Conclusion: Comparison of laser-Doppler vibrometry results and audiometry may be a sensitive and selective indicator of ossicular pathologic conditions as well as a useful tool for investigating middle ear function.