Assessment of serum level cholinesterase as a biomarker of liver cirrhosis in Egyptian cirrhotic patients
Assessment of serum level cholinesterase as a biomarker of liver cirrhosis in Egyptian cirrhotic patients
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DOI：
10.4081/gi.2017.6914
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发表时间：
2017-01-01
影响因子：
2.9
通讯作者：
Obaia, Eman
中科院分区：
文献类型：
--
作者：
Amin, Mona A.;El-Shahat, Marwa E.;Obaia, Eman
血清胆碱酯酶水平与肝病的严重程度密切相关。本文旨在探讨血清胆碱酯酶对肝储备功能的评价价值。肝硬化患者90例，健康对照组30例。根据Child评分将肝硬化患者分为三组：Child A型肝硬化、Child B型肝硬化和Child C型肝硬化。对患者进行临床评价、实验室分析、腹部超声检查。测定血清胆碱酯酶，计算Child和终末期肝病模型（MELD）评分。正常对照组血清胆碱酯酶水平高于肝硬化组、肝硬化组和对照组，中位数分别为17，410（12，111 ~ 21，774），7528（5200-9856），6021（4500-7542），3828.5（1541-6060），P
Serum cholinesterase levels are closely correlated with the severity of liver disease. The aim of the paper was to assess the value of serum cholinesterase in evaluating liver reserve function in cirrhotic patients. 90 patients with liver cirrhosis and thirty healthy control group were included. Liver cirrhosis patients were classified according to child score into three equal groups: Child A liver cirrhosis, Child B liver cirrhosis and Child C liver cirrhosis. Patients were subjected to clinical evaluation, laboratory analysis, abdominal U/S. Measuring serum cholinesterase, and Calculation of both Child and model of end stage liver disease (MELD) scores. The level of serum cholinesterase was higher in control group than the three groups of liver cirrhosis with median (IQR) 17,410 (12,111-21,774), 7528 (5200-9856), 6021 (4500-7542), 3828.5 (1541-6060), respectively P