Elevated protein kinase C alpha expression may be predictive of tamoxifen treatment failure.
Elevated protein kinase C alpha expression may be predictive of tamoxifen treatment failure.
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DOI:
10.1038/sj.bjc.6600923
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发表时间:
2003-05-06
影响因子:
8.8
通讯作者:
中科院分区:
文献类型:
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We previously reported that stable transfection of protein kinase C alpha (PKCα) into T47D human breast cancer cells results in tamoxifen (TAM)-resistant tumour growth. Relevance of PKCα expression in clinical specimens was determined by comparing PKCα expression in tumours from patients exhibiting disease recurrence with patients remaining disease-free following TAM treatment. Our results suggest that PKCα expression may predict TAM treatment failure.
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DOI:
10.1093/jnci/93.22.1714
发表时间:
2001-11-21
期刊:
JOURNAL OF THE NATIONAL CANCER INSTITUTE
影响因子:
--
作者:
Song, RXD;Mor, G;Santen, RJ
通讯作者:
Santen, RJ
DOI:
10.1093/jnci/92.23.1926
发表时间:
2000-12-06
期刊:
JOURNAL OF THE NATIONAL CANCER INSTITUTE
影响因子:
--
作者:
Schiff, R;Reddy, P;Osborne, CK
通讯作者:
Osborne, CK
影响因子:
3.8
作者:
Brunner, N;SpangThomsen, M;Cullen, K
通讯作者:
Cullen, K
影响因子:
3.9
作者:
Fernandez, P;Wilson, C;Safe, SH
通讯作者:
Safe, SH
影响因子:
4.8
作者:
Shim, WS;Conaway, M;Santen, RJ
通讯作者:
Santen, RJ