Chemical Nanosensors Based on Composite Molecularly Imprinted Polymer Particles and Surface-Enhanced Raman Scattering
Chemical Nanosensors Based on Composite Molecularly Imprinted Polymer Particles and Surface-Enhanced Raman Scattering
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DOI：
10.1002/adma.200904442
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发表时间：
2010-06-04
影响因子：
29.4
通讯作者：
Haupt, Karsten
中科院分区：
文献类型：
--
作者：
Bompart, Marc;De Wilde, Yannick;Haupt, Karsten
描述了一种亚微米核壳复合设计的化学纳米传感器，该传感器基于聚合物核，用于特定分析物识别的分子印迹聚合物（MIP）壳，以及用于信号放大的金纳米颗粒中间层。在单个纳米传感器上的SERS测量对β受体阻滞剂心得安的检测限为10(-7)M，比普通MIP球低几个数量级。
Chemical nanosensors with a submicrometer core-shell composite design, based on a polymer core, a molecularly imprinted polymer (MIP) shell for specific analyte recognition, and an interlayer of gold nanoparticles for signal amplification, are described. SERS measurements on single nanosensors yield detection limits of 10(-7) M for the beta-blocker propranolol, several orders of magnitude lower than on plain MIP spheres.