Gin → Arg 191 polymorphism of paraoxonase and Parkinson's disease
Gin → Arg 191 polymorphism of paraoxonase and Parkinson's disease
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DOI：
10.1159/000022868
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发表时间：
1999-01-01
期刊：
影响因子：
1.8
通讯作者：
Schwartz, E
中科院分区：
文献类型：
--
作者：
Akhmedova, S;Anisimov, S;Schwartz, E
我们研究了圣彼得堡人群中对氧磷酶(PON1)中的Gln--&Gt；Arg 191多态，在帕金森氏病(PD)的三个临床分化组和症状性震颤组中。本文提出了一种新的Gln--&Arg 191 PON1基因分型方法。与对照组相比，两组研究没有显著差异。
We investigated the Gln --> Arg 191 polymorphism-in paraoxonase (PON1) in St. Petersburg population, in three clinically differentiated groups of patients with Parkinson's disease (PD) and in the symptomatic tremor group. A new approach for Gln --> Arg 191 PON1 polymorphism genotyping is suggested. No significant differences in the groups studies as compared to the controls was observed.