Cerebral organization of component processes in reading

Cerebral organization of component processes in reading
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DOI:
10.1093/brain/119.4.1221
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发表时间:
1996-08-01
期刊:
影响因子:
14.5
通讯作者:
Gore, JC
Gore, JC
中科院分区:
医学1区
文献类型:
--
作者:
Pugh, KR;Shaywitz, BA;Gore, JC

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采用功能磁共振成像(fMRI)技术研究了阅读过程中单词识别过程的脑组织结构。38名受试者(19名男性和19名女性)在视觉(行判断),正字法(字母大小写判断),语音(非词韵判断)和语义(语义类别判断)任务中的fMRI信号强度的变化进行了测量。为了验证结构和功能之间的关系,采用了多重减法策略。正字法处理的最大需求外纹网站,语音处理的额和颞的网站上的数量,和词汇语义处理是最强烈的中间和上级颞网站。阅读相关过程的大脑组织也存在显著的性别差异。
The cerebral organization of word identification processes in reading was examined using functional magnetic resonance imaging (fMRI). Changes in fMRI signal intensities were measured in 38 subjects (19 males and 19 females) during visual (line judgement), orthographic (letter case judgement), phonological (nonword rhyme judgement) and semantic (semantic category judgement) tasks. A strategy of multiple subtractions was employed in order to validate relationships between structure and function. Orthographic processing made maximum demands on extrastriate sites, phonological processing on a number of frontal and temporal sites, and lexical-semantic processing was most strongly associated with middle and superior temporal sites. Significant sex differences in the cerebral organization of reading-related processes were also observed.