VITAMIN-D DEFICIENCY IN THE MORBIDLY OBESE
VITAMIN-D DEFICIENCY IN THE MORBIDLY OBESE
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DOI：
10.1381/096089293765559142
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发表时间：
1993-11-01
期刊：
影响因子：
2.9
通讯作者：
SCRUGGS, D
中科院分区：
文献类型：
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作者：
BUFFINGTON, C;WALKER, B;SCRUGGS, D
虽然胃旁路手术后维生素D缺乏症已被充分证明，但很少有关于非手术病态肥胖患者维生素D状况的研究。我们检查了60例病态肥胖女性术前的25-羟维生素D（25-OHD）水平;其中62%的25-OHD水平低于正常范围（16-74 ng/ml），这与血清钙或磷降低、肝或肾功能障碍无关，与患者年龄无显著相关性。然而，25-OHD水平与体重显著（p < 0.0001）和负相关（r =-0.49）。这些数据表明，低维生素D可能与肥胖本身有关。当在减肥手术后的患者中发现维生素D缺乏症时，可能不是由手术引起的，因为它可能在手术前就存在一定程度。
Although vitamin D deficiency has been well-documented following gastric bypass surgery, there are few studies of vitamin D status in the non-operative morbidly obese patient. We examined 25-hydroxyvitamin D (25-OHD) levels in 60 morbidly obese pre-operative females; 62% of them had 25-OHD levels below normal range (16-74 ng/ml) which were not associated with reductions in serum calcium or phosphorus, liver or kidney dysfunction, and were not significantly correlated to patients' age. However, 25-OHD levels were significantly (p < 0.0001) and negatively correlated to body mass (r = - 0.49). These data suggest that low vitamin D may be associated with obesity per se. Hypovitaminosis D, when it is found in post-bariatric surgery patients, may not be caused by the surgery since it may have been present to some degree pre-operatively.