Clinical Features of Delusional Jealousy in Elderly Patients With Dementia
Clinical Features of Delusional Jealousy in Elderly Patients With Dementia
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DOI：
10.4088/jcp.14m09018
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发表时间：
2015-06-01
影响因子：
5.3
通讯作者：
Ikeda, Manabu
中科院分区：
文献类型：
--
作者：
Hashimoto, Mamoru;Sakamoto, Shinichi;Ikeda, Manabu
目的：妄想性嫉妒是一种精神病性综合症，其特征是相信配偶的不忠，并达到妄想的强度。虽然妄想性嫉妒被描述为器质性精神病，但人们对妄想性嫉妒在痴呆中的实际作用知之甚少。本研究的目的是探讨妄想嫉妒的临床特征和妄想嫉妒在痴呆患者中产生的可能机制。方法：我们研究了208例连续门诊痴呆患者（诊断依据DSM-III-R标准，平均[SD]年龄77.0[8.0]岁，研究时间：2011年9月- 2012年8月）。妄想型嫉妒被定义为一种源于病态嫉妒的错误信念，使患者相信他或她的配偶不忠。比较了阿尔茨海默病、路易体痴呆和血管性痴呆患者妄想性嫉妒的患病率。比较有嫉妒妄想和无嫉妒妄想患者的一般特征。此外，对每位妄想嫉妒患者及其主要照顾者进行访谈，了解该综合征的临床特征。结果：208例痴呆患者中有18例（8.7%）表现为妄想性嫉妒。伴路易体痴呆患者妄想嫉妒的患病率（26.3%）显著高于阿尔茨海默病患者（5.5%）(P
Objective: Delusional jealousy is a psychotic syndrome characterized by a belief in the infidelity of one's spouse that reaches delusional intensity. Although delusional jealousy has been described in relation to organic psychosis, little is known concerning the actual role of delusional jealousy in dementia. The aim of the present study was to investigate the clinical features of delusional jealousy and possible mechanisms whereby delusional jealousy arises in patients with dementia.Method: We studied 208 consecutive outpatients with dementia (diagnosis based on DSM-III-R criteria; mean [SD] age of 77.0 [8.0] years; study period: September 2011-August 2012). Delusional jealousy was defined as a false belief derived from a pathological jealousy that makes the patient believe that his or her spouse is unfaithful. The prevalence of delusional jealousy was compared between Alzheimer's disease, dementia with Lewy bodies, and vascular dementia. Patients with and without delusional jealousy were compared in terms of general characteristics. In addition, each patient with delusional jealousy and their primary caregivers were interviewed about the clinical features of the syndrome.Results: Of the 208 patients with dementia, 18 (8.7%) showed delusional jealousy. The prevalence of delusional jealousy in patients who had dementia with Lewy bodies (26.3%) was significantly higher than that in patients with Alzheimer's disease (5.5%) (P