Heterotopic ossification of the shoulder joint following spinal cord injury: an analysis of 21 cases after single-dose radiation therapy
Heterotopic ossification of the shoulder joint following spinal cord injury: an analysis of 21 cases after single-dose radiation therapy
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DOI：
10.1038/sc.2015.182
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发表时间：
2016-04-01
期刊：
影响因子：
2.2
通讯作者：
Aach, M.
中科院分区：
文献类型：
--
作者：
Citak, M.;Grasmuecke, D.;Aach, M.
研究设计：回顾图表回顾。目的：影响髋关节的异位骨化(HO)是创伤性脊髓损伤患者的常见症状。然而，肩部HO的发生率相当罕见。在此背景下，我们报告了13例患者的结果，共21例肩关节HO和单次剂量放射治疗。单位：德国波鸿鲁尔大学伯格曼希尔·波鸿BG大学波鸿医院脊髓损伤科和普通外科。结果：在住院期间的最后一次随访时，平均肩部屈曲92.1度，平均外展94.5度。平均外旋26.4度。无HO复发，无放射治疗相关不良反应。结论：单次剂量放射治疗脊髓损伤所致肩关节HO是一种有效、可靠的治疗方法，但与放射治疗相关的继发性副作用风险尚不清楚。
Study design: Retrospective chart review.Objectives: Heterotopic ossification (HO) affecting the hips is a common complaint of patients suffering traumatic spinal cord injury. However, the incidence of HO of the shoulder is considerably rare. In this context, we report on our results of 13 patients with a total of 21 cases of shoulder HO and single-dose radiation therapy.Setting: Department of Spinal Cord Injury and Department of General and Trauma Surgery, BG-University Hospital Bergmannsheil Bochum, Ruhr-University Bochum, Germany.Methods: The study group consists of 12 male and 1 female patient with a mean age of 55.5 years (range from 24 to 81 years; s.d.=14.5). Primary outcome measures were defined as the number of HO relapses and the number of side or adverse effects in relation to the radiation therapy.Results: At the time of latest follow-up during hospitalization, the mean shoulder flexion was 92.1 degrees while mean abduction was 94.5 degrees. The average external rotation was 26.4 degrees. No HO recurrence occurred and none of the patients suffered any adverse effects related to radiation therapy.Conclusions: In conclusion, single-dose radiation therapy in the treatment of shoulder HO due to spinal cord injury is an effective and reliable method, although the risk of secondary side effects related to the radiation therapy remain unknown.