Natural orifice transluminal endoscopic surgery gastroenterostomy with a biflanged lumen-apposing stent: first clinical experience (with videos)

Natural orifice transluminal endoscopic surgery gastroenterostomy with a biflanged lumen-apposing stent: first clinical experience (with videos)
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DOI:
10.1016/j.gie.2014.09.039
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发表时间:
2015-01-01
影响因子:
7.7
通讯作者:
Berdah, Stephane
Berdah, Stephane
中科院分区:
医学1区
文献类型:
--
作者:
Barthet, Marc;Binmoeller, Kenneth F.;Berdah, Stephane

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背景:我们建立了生猪自然孔腔内镜手术 (NOTES) 胃肠道吻合术的可行性和安全性。该方法在 3 名患者中进行。目的:为患者建立 NOTES 胃十二指肠吻合术。设计:病例系列。设置:法国和美国大型学术医院的两个三级护理转诊中心。患者:难治性良性十二指肠狭窄和恶性十二指肠梗阻患者。干预:使用内腔并置支架进行 NOTES GI 吻合术。主要结果测量:胃出口梗阻消失。结果:除 1 起轻微不良事件外,所有 3 次手术在技术上均成功且平安无事。随访期间未出现支架闭塞或移位的情况。所有患者恢复正常饮食。局限性:小病例系列。结论:NOTES胃肠吻合术在人类中是可行且安全的。有必要进行前瞻性试点研究。
Background: We established feasibility and safety for natural orifice transluminal endoscopic surgery (NOTES) GI anastomosis with a lumen-apposing stent in live pigs. This approach was performed in 3 patients.Objective: Creation of a NOTES gastroduodenal anastomosis in patients.Design: Case series.Setting: Two tertiary-care referral centers at large academic hospitals in France and in the United States.Patients: Patients with refractory benign duodenal stenosis and malignant duodenal obstruction.Intervention: NOTES GI anastomosis with a lumen-apposing stent.Main Outcome Measurements: Disappearence of gastric outlet obstruction.Results: All 3 procedures were technically successful and uneventful, except 1 minor adverse event. There were no instances of stent occlusion or migration during follow-up. All patients resumed a normal diet.Limitations: Small case series.Conclusion: NOTES gastroenteric anastomosis is feasible and safe in humans. A prospective pilot study is warranted.