Cariogenicity features of Streptococcus mutans in presence of rubusoside.
Cariogenicity features of Streptococcus mutans in presence of rubusoside.
复制标题
DOI：
10.1186/s12903-016-0212-1
复制
发表时间：
2016-05-11
期刊：
影响因子：
2.9
通讯作者：
He K
中科院分区：
文献类型：
--
作者：
Chu J;Zhang T;He K
减少龋齿的一个有希望的方法是在食物中使用蔗糖替代品。甜茶苷是从植物甜茶（RubrussuavissimusS.）李你（蔷薇科），比蔗糖更甜。本研究旨在探讨甜茶苷对变形链球菌生长、产酸及玻璃粘附的影响。用分光光度计测定变形链球菌培养液在540 nm处的光密度，研究甜茶苷对变形链球菌生长和玻璃表面粘附的影响。通过测量培养物的pH值来确定甜茶苷对变形链球菌产酸性的影响。设计蔗糖、葡萄糖、麦芽糖、果糖和木糖醇与甜茶苷进行比较。S.除木糖醇组（P > 0.05）外，甜茶苷组变形杆菌生长量显著低于蔗糖、葡萄糖、麦芽糖和果糖组（P <0.05）。蔗糖处理S.变形链球菌表现出最高的粘附玻璃，和悬钩子苷处理的S。变异株的比例最低。S.悬钩子苷显著降低了变形菌对玻璃表面的粘附和对蔗糖的产酸性。甜茶苷可能具有作为非致龋、无热量甜味剂的一些潜力。
One promising way of reducing caries is by using sucrose substitutes in food. rubusoside is a prototype sweet substance isolated from the leaves of the plant Rubrus suavissimus S. Lee. (Rosaceae), and is rated sweeter than sucrose. The purpose of this study was to investigate the effects of rubusoside on Streptococcus mutans growth, acidogenicity, and adherence to glass in vitro. The effects of rubusoside on the growth and glass surface adhering of Streptococcus mutans were investigated by measuring the optical density of the culture at 540 nm with a spectrophotometer. Rubusoside influence on Streptococcus mutans acidogenicity was determined by measuring the pH of the culture. Sucrose, glucose, maltose, fructose and xylitol were designed to compare with rubusoside. S. mutans growth in the rubusoside-treated group was significantly lower than that in the sucrose, glucose, maltose and fructose groups (p < 0.05) except for xylitol group (p > 0.05). Sucrose-treated S. mutans exhibited the highest adherence to glass, and rubusoside-treated S. mutans exhibited the lowest. S. mutans adherence to a glass surface and acidogenicity with sucrose were significantly reduced by rubusoside. Rubusoside may have some potential as a non-cariogenic, non-caloric sweetener.