Rapidly rising breast cancer incidence rates among Asian-American women
Rapidly rising breast cancer incidence rates among Asian-American women
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DOI：
10.1002/ijc.10415
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发表时间：
2002-06-10
影响因子：
6.4
通讯作者：
Ross, RK
中科院分区：
文献类型：
--
作者：
Deapen, D;Liu, LH;Ross, RK
近年来，乳腺癌的发病率在相对较短的时间内波动;检查这些模式可以为预防计划提供病因学线索和方向。亚裔美国女性通常被认为比其他种族群体患乳腺癌的风险更低。然而，他们的比率通常是基于亚裔人口的聚集，这可能掩盖了风险的重要种族差异。对种族特异性发病率趋势的详细分析将提供比合并种族时更多的信息。加州的洛杉矶县是美国人口最多的县，也可能是种族最多样化的县，拥有大量多种族的亚裔美国人。利用洛杉矶癌症监测项目的数据，对浸润性女性乳腺癌发病率的趋势进行了研究，该项目是一个覆盖该县的基于人口的癌症登记处。尽管总体乳腺癌发病率在20世纪80年代末和90年代初保持稳定，但最近5年的数据表明，50岁以上的亚裔美国人和非西班牙裔白色妇女的发病率可能再次增加（估计年百分比变化分别为6.3%，p < 0.05和1.5%，p < 0.05），尽管黑人和西班牙裔妇女几乎没有变化。亚裔美国人族群的浸润性乳腺癌发病率是异质性的，并且对大多数人来说，发病率正在上升。在洛杉矶县，日裔美国妇女的比率自1988年以来迅速上升，现在接近非西班牙裔白色妇女的比率。菲律宾人的比例历史上一直高于其他亚裔美国人，但没有像日本妇女那样迅速增长，但仍然相对较高。日本和菲律宾血统的女性患乳腺癌的风险是中国和韩国女性的两倍。亚洲妇女在其本国的乳腺癌发病率通常较低，移民到美国后，乳腺癌发病率通常会增加。种族特异性发病率显示，日裔美国人是第一批大量移民到洛杉矶县的亚裔人口，也是文化适应程度最高的人群，他们的乳腺癌发病率迅速上升。如果最近的趋势继续下去，洛杉矶县的日裔美国人比率可能已经超过了非西班牙裔白人。(C)2002 Wiley-Liss，Inc.
In recent years, breast cancer incidence rates have fluctuated over relatively short time spans; examination of these patterns can provide etiologic clues and direction for prevention programs. Asian-American women are generally considered to be at lower risk of breast cancer than other ethnic groups. However, their rates are typically based on an aggregation of ethnic Asian populations, which may obscure important ethnic differences in risk. Detailed analyses of the trends in ethnic-specific incidence rates will provide more information than when ethnicities are combined. Los Angeles County, California, the most populous and probably the most ethnically diverse county in the United States, has a large multi-ethnic Asian-American population. Trends in invasive female breast cancer incidence were examined using data from the Los Angeles Cancer Surveillance Program, the population-based cancer registry covering the County. Athough overall breast cancer incidence rates remained stable in the late 1980s and early 1990s, data for the most recent 5-year period suggest that incidence may again be increasing for Asian-American and non-Hispanic white women over age 50 (estimated annual percent change = 6.3%, p < 0.05 and 1.5%, p < 0.05, respectively), although little change has occurred among black and Hispanic women. Invasive breast cancer incidence rates for Asian-American ethnic groups are heterogeneous and, for most, are increasing. In Los Angeles County, rates for Japanese-American women have increased rapidly since 1988 and are now approaching rates for non-Hispanic white women. Rates among Filipinas, who have historically had higher rates than their other Asian-American counterparts, are not increasing as rapidly as rates for Japanese women, but remain relatively high. Breast cancer risk among women of Japanese and Filipino ancestry is twice that of Chinese and Korean women. Asian women, who commonly have low breast cancer rates in their native countries, typically experience increasing breast cancer incidence after immigrating to the United States. Ethnic-specific incidence rates show that Japanese-Americans, the first Asian population to immigrate to Los Angeles County in large numbers and the most acculturated, have experienced a rapid increase in breast cancer incidence. Japanese-American rates in Los Angeles County may have already surpassed those of non-Hispanic whites if recent trends have continued unabated. (C) 2002 Wiley-Liss, Inc.